Background

Shoulder disorders, including frozen shoulder, bursitis, and rotator cuff lesions, are common musculoskeletal problems in patients with Parkinson disease (PD). Because musculoskeletal ultrasound (US) can clearly image shoulder joints, we aimed to evaluate shoulder joints using US in patients with PD and healthy participants and correlation between US and PD severity.

Methods

This is a prospective case-control study. 50 patients with PD and 50 healthy subjects from the outpatient department were administered US for bilateral shoulders. For data analysis, we chose the more severely affected side in the PD group for matching with the corresponding shoulder in the control group according to age, sex, and body mass index. Pain and disability were measured using the Visual Analogue Scale (VAS) for pain, Shoulder Pain and Disability Index (SPADI), and the Shoulder Disability Questionnaire (SDQ).

Results

The PD group had higher VAS pain scores during activity (p = 0.003) and rest (p < 0.001), as well as the SPADI and SDQ scores (p < 0.001). In US findings, biceps long head tendon sheath effusion (p = 0.001), humeral head cortical irregularity (p = 0.012), and abnormality in the supraspinatus tendon (p = 0.003) were significantly greater in the PD group. Intra-group analysis in the PD group demonstrated a significant difference in passive flexion (p = 0.019) and supraspinatus tendinopathy (p = 0.033) on US examination during different disease stages.

Conclusions

Patients with PD had more supraspinatus tendinopathy on US findings than control subjects. The lesion was significantly associated with disease severity.

Clinical trial number

NCT02702232.

中文翻译：

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帕金森病患者肩部超声影像学表现

背景

肩部疾病，包括肩周炎、滑囊炎和肩袖病变，是帕金森病(PD)患者常见的肌肉骨骼问题。由于肌肉骨骼超声 (US) 可以清晰地对肩关节进行成像，因此我们的目的是使用 US 评估 PD 患者和健康参与者的肩关节，以及 US 和 PD 严重程度之间的相关性。

方法

这是一项前瞻性病例对照研究。门诊50例PD患者和50例健康受试者接受双侧肩部超声检查。为了进行数据分析，我们根据年龄、性别和体重指数，选择PD组中受影响较严重的一侧与对照组中相应的肩部进行匹配。使用疼痛视觉模拟量表（VAS）、肩部疼痛和残疾指数（SPADI）以及肩部残疾问卷（SDQ）来测量疼痛和残疾。

结果

PD 组在活动时 (p = 0.003) 和休息时 (p < 0.001) 具有较高的 VAS 疼痛评分，以及 SPADI 和 SDQ 评分 (p < 0.001)。在超声检查结果中， PD 组的二头肌长头腱鞘积液（p = 0.001）、肱骨头皮质不规则（p = 0.012）和冈上肌腱异常（p = 0.003）显着更高。PD 组的组内分析表明，不同疾病阶段超声检查中被动屈曲 (p = 0.019) 和冈上肌腱病 (p = 0.033) 存在显着差异。

结论

根据超声检查结果，PD 患者比对照受试者有更多冈上肌腱病变。病变与疾病严重程度显着相关。

临床试验编号

NCT02702232。