Nucleation is widely present in nature, from food production to haze generation. Owe to the spatiotemporal limitation in catching the dynamic characters of nucleation process, the theoretical development and the control technique of nucleation is far behind the demand. Here we report a strategy of controlling nucleation process via manipulating the collision of nucleation units, with the aim of disclosing the mechanism dominating the nucleation process. Silver nucleation is simulated at different collision conditions which is regulated by chemicals diffusion and reaction rate. It is found that the nucleation rate has a good linear relationship with the collision frequency, suggesting a collision dependent nucleation model. This model is evaluated by particles-based silver aggregation and validated by experiments conducted in an in-situ electron microscopy. Furthermore, the model is applied to the improved synthesis of silver catalysts for selective partial oxidation of ethylene.

从食物生产到雾霾产生，成核现象广泛存在于自然界中。由于在捕捉成核过程的动态特征方面的时空限制，成核的理论发展和控制技术远远落后于需求。在这里，我们报告了一种通过操纵成核单元的碰撞来控制成核过程的策略，目的是揭示主导成核过程的机制。在不同的碰撞条件下模拟银成核，该碰撞条件受化学物质扩散和反应速率的调节。发现成核速率与碰撞频率具有良好的线性关系，表明成核模型与碰撞相关。该模型通过基于颗粒的银聚集进行评估，并通过在原位电子显微镜。此外，该模型还应用于乙烯选择性部分氧化银催化剂的改进合成。