Self-powered, highly unobtrusive, low-cost and accurate arterial pulse wave monitoring devices need to be developed to enable cost-efficient monitoring of entire cardiovascular disease risk groups. We report the development of a scalable fabrication process for a highly unobtrusive piezoelectric ultra-thin (t ~ 4,2 µm) e-tattoo arterial pulse wave sensor which utilizes only transparent and biocompatible polymer-based materials. The ferroelectric performance of the ultra-thin P(VDF-TrFE) material layer is optimized through the use of crosslinked PEDOT:PSS electrodes; this results in ~70 % and ~34 % improvements in remanent polarization (P_r) and coercive field (E_c), respectively, when compared to the sensors with pristine PEDOT:PSS electrodes. The ultra-thin form factor enables access to the high bending mode sensitivity of the P(VDF-TrFE) material layer; the maximum sensitivity value achieved in uniaxial and multiaxial bending is ~1700 pC N^-1, which is ~50 times higher than the measured normal mode sensitivity. The increased sensitivity is linked to a specific set of direct piezoelectric coefficients using combination of experimental results, statistical analysis and finite element modeling. Finally, the accuracy of the e-tattoo sensor is demonstrated in the non-invasive measurement of radial artery pulse wave by comparing the signal to that obtained with reference device from 7 study subjects.

需要开发自供电、高度隐蔽、低成本和准确的动脉脉搏波监测设备，以实现对整个心血管疾病风险组的经济高效监测。我们报告了一种高度不显眼的压电超薄 (t ~ 4,2 µm) 电子纹身动脉脉搏波传感器的可扩展制造工艺的开发，该传感器仅使用透明且生物相容的聚合物基材料。通过使用交联的 PEDOT:PSS 电极优化了超薄 P(VDF-TrFE) 材料层的铁电性能；这导致剩余极化 (P _r ) 和矫顽场 (E _c) 分别与具有原始 PEDOT:PSS 电极的传感器相比。超薄的外形尺寸可以实现 P(VDF-TrFE) 材料层的高弯曲模式灵敏度；在单轴和多轴弯曲中获得的最大灵敏度值约为 1700 pC N ^-1，比测得的正常模式灵敏度高约 50 倍。使用实验结果、统计分析和有限元建模的组合，提高的灵敏度与一组特定的直接压电系数相关联。最后，通过将来自 7 个研究对象的信号与使用参考设备获得的信号进行比较，证明了电子纹身传感器在无创测量桡动脉脉搏波中的准确性。