Natural plant extracts are primarily used as raw materials in the cosmetic and perfumery industry. However, adulterations with petrochemical products are occurring in the market, leading to non-100% natural products. Several analytical techniques such as impurity detection or enantioselective ratio assessments have been previously described as good indicators to detect any addition of synthetic products, but these techniques are ineffective with novel type of synthetic pathways such as semisynthesis. In order to improve authentication, development of advanced analytical strategies such as δ¹⁸O stable isotopic ratios assessment was tested on spearmint, cinnamon and bitter almond essential oils major metabolites (carvone, (E)-cinnamaldehyde, and benzaldehyde). Natural δ¹⁸O mean values (δ¹⁸O_Carvone = 18.4‰; δ¹⁸O_{Cinnamaldehyde} = 13.9‰; δ¹⁸O_Benzaldehyde = 16.5‰) were found to be higher than semisynthetic origin for the 3 studied molecules (δ¹⁸O_Carvone = 9.2‰; δ¹⁸O_{Cinnamaldehyde} = 8.8‰; δ¹⁸O_Benzaldehyde = 10.9‰). These measurements proved to be efficient to discriminate natural and semisynthetic origins of these components and therefore potentially lead to a novel way to authenticate natural products.

天然植物提取物主要用作化妆品和香水行业的原料。然而，市场上存在掺假石化产品的情况，导致产品不是 100% 天然的。杂质检测或对映选择性比率评估等几种分析技术先前已被描述为检测任何合成产物添加的良好指标，但这些技术对新型合成途径（如半合成）无效。为了改进鉴定，对留兰香、肉桂和苦杏仁精油的主要代谢物（香芹酮、(E)-肉桂醛和苯甲醛）测试了δ ^{18 O 稳定同位素比率评估等先进分析策略的开发。}天然^δ18O 平均值（δ ¹⁸ O_香芹酮 = 18.4‰；δ ¹⁸ O_肉桂醛 = 13.9‰；δ ¹⁸ O_苯甲醛 = 16.5‰）被发现高于 3 个研究分子的半合成来源（δ ¹⁸ O_香芹酮 = 9.2‰ ；δ 18 O 苯甲醛 = 16.5‰）。 δ ¹⁸ O_肉桂醛 =8.8‰；δ ¹⁸ O_苯甲醛 =10.9‰）。事实证明，这些测量可有效区分这些成分的天然来源和半合成来源，因此可能会产生一种鉴定天然产品的新方法。