当前位置: X-MOL 学术Chem. Rev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Spectrochemistry of Firefly Bioluminescence
Chemical Reviews ( IF 51.4 ) Pub Date : 2022-08-04 , DOI: 10.1021/acs.chemrev.1c01047
Marieh B Al-Handawi 1 , Srujana Polavaram 1 , Anastasiya Kurlevskaya 1 , Patrick Commins 1 , Stefan Schramm 2 , César Carrasco-López 3 , Nathan M Lui 4 , Kyril M Solntsev 5 , Sergey P Laptenok 6 , Isabelle Navizet 7 , Panče Naumov 1, 8
Affiliation  

The chemical reactions underlying the emission of light in fireflies and other bioluminescent beetles are some of the most thoroughly studied processes by scientists worldwide. Despite these remarkable efforts, fierce academic arguments continue around even some of the most fundamental aspects of the reaction mechanism behind the beetle bioluminescence. In an attempt to reach a consensus, we made an exhaustive search of the available literature and compiled the key discoveries on the fluorescence and chemiluminescence spectrochemistry of the emitting molecule, the firefly oxyluciferin, and its chemical analogues reported over the past 50+ years. The factors that affect the light emission, including intermolecular interactions, solvent polarity, and electronic effects, were analyzed in the context of both the reaction mechanism and the different colors of light emitted by different luciferases. The collective data points toward a combined emission of multiple coexistent forms of oxyluciferin as the most probable explanation for the variation in color of the emitted light. We also highlight realistic research directions to eventually address some of the remaining questions related to firefly bioluminescence. It is our hope that this extensive compilation of data and detailed analysis will not only consolidate the existing body of knowledge on this important phenomenon but will also aid in reaching a wider consensus on some of the mechanistic details of firefly bioluminescence.

中文翻译:

萤火虫生物发光的光谱化学

萤火虫和其他生物发光甲虫发光的化学反应是全世界科学家研究最深入的过程。尽管做出了这些非凡的努力,但围绕甲虫生物发光背后反应机制的一些最基本方面的激烈学术争论仍在继续。为了达成共识,我们对现有文献进行了详尽的搜索,并汇编了过去 50 多年报道的发光分子萤火虫氧化荧光素及其化学类似物的荧光和化学发光光谱化学的关键发现。影响发光的因素,包括分子间相互作用、溶剂极性和电子效应,在反应机制和不同荧光素酶发出的不同颜色的光的背景下进行了分析。集体数据指向多种共存形式的氧化荧光素的组合发射,作为发射光颜色变化的最可能解释。我们还强调了现实的研究方向,以最终解决与萤火虫生物发光相关的一些剩余问题。我们希望,这种广泛的数据汇编和详细的分析不仅能巩固关于这一重要现象的现有知识体系,而且有助于就萤火虫生物发光的一些机制细节达成更广泛的共识。集体数据指向多种共存形式的氧化荧光素的组合发射,作为发射光颜色变化的最可能解释。我们还强调了现实的研究方向,以最终解决与萤火虫生物发光相关的一些剩余问题。我们希望,这种广泛的数据汇编和详细的分析不仅能巩固关于这一重要现象的现有知识体系,而且有助于就萤火虫生物发光的一些机制细节达成更广泛的共识。集体数据指向多种共存形式的氧化荧光素的组合发射,作为发射光颜色变化的最可能解释。我们还强调了现实的研究方向,以最终解决与萤火虫生物发光相关的一些剩余问题。我们希望,这种广泛的数据汇编和详细的分析不仅能巩固关于这一重要现象的现有知识体系,而且有助于就萤火虫生物发光的一些机制细节达成更广泛的共识。
更新日期:2022-08-04
down
wechat
bug