During the first meeting of the World Health Organization (WHO) in 1973, pulmonary hypertension (PH) was defined as mean pulmonary artery pressure (mPAP) ≥25 mmHg measured by right heart catheterisation [1]. This criterion was chosen arbitrarily and was founded on the premise that mPAP at rest in a supine position does not exceed 15 mmHg 2]. In 2009, the landmark paper of Kovacs et al. [3] provided scientific evidence for this statement and showed that normal mPAP at rest was 14 mmHg, with an upper limit of normal of 20 mmHg. In addition, accumulating data has indicated that patients with mPAP ≥19 mmHg but below the haemodynamic threshold of 25 mmHg are at increased mortality risk [4–6].

在 1973 年世界卫生组织 (WHO) 的第一次会议上，肺动脉高压 (PH) 被定义为通过右心导管插入术测量的平均肺动脉压 (mPAP) ≥25 mmHg [1]。该标准是任意选择的，并且建立在仰卧位时 mPAP 不超过 15 mmHg 2] 的前提下。2009年，K的标志性论文奥瓦克斯 等人。[3] 为该声明提供了科学证据，表明静息时的正常 mPAP 为 14 mmHg，正常上限为 20 mmHg。此外，越来越多的数据表明，mPAP ≥19 mmHg 但低于血流动力学阈值 25 mmHg 的患者死亡风险增加 [4-6]。