Despite its potential scalability, little is known about the outcomes of internet-based cognitive behaviour therapy (iCBT) for post-traumatic stress disorder (PTSD) when it is provided with minimal guidance from a clinician.

To evaluate the outcomes of minimally guided iCBT for PTSD in a randomised control trial (RCT, Study 1) and in an open trial in routine community care (Study 2).

A RCT compared the iCBT course (n=21) to a waitlist control (WLC, n=19) among participants diagnosed with PTSD. The iCBT group was followed up 3 months post-treatment. In Study 2, treatment outcomes were evaluated among 117 adults in routine community care. PTSD symptom severity was the primary outcome in both studies, with psychological distress and co-morbid anxiety and depressive symptoms providing secondary outcomes.

iCBT participants in both studies experienced significant reductions in PTSD symptom severity from pre- to post-treatment treatment (within-group Hedges’ g=.72–1.02), with RCT findings showing maintenance of gains at 3-month follow-up. The WLC group in the RCT also significantly improved, but Study 1 was under-powered and the medium between-group effect favouring iCBT did not reach significance (g=0.64; 95% CI, –0.10–1.38).

This research provides preliminary support for the utility of iCBT for PTSD when provided with minimal clinician guidance. Future studies are needed to clarify the effect of differing levels of clinician support on PTSD iCBT outcomes, as well as exploring how best to integrate iCBT into large-scale, routine clinical care of PTSD.

尽管具有潜在的可扩展性，但对于基于互联网的认知行为疗法 (iCBT) 治疗创伤后应激障碍 (PTSD) 的结果知之甚少，但在临床医生提供的指导很少的情况下。

在一项随机对照试验（RCT，研究 1）和一项常规社区护理的开放试验（研究 2）中评估微量引导 iCBT 治疗 PTSD 的结果。

一项 RCT在诊断为 PTSD 的参与者中将 iCBT 课程（n = 21）与候补名单对照（WLC，n = 19）进行了比较。iCBT组在治疗后3个月进行随访。在研究 2 中，对 117 名接受常规社区护理的成年人的治疗结果进行了评估。创伤后应激障碍症状严重程度是两项研究的主要结果，心理困扰和共病焦虑和抑郁症状提供次要结果。

两项研究中的 iCBT 参与者经历了从治疗前到治疗后的 PTSD 症状严重程度显着降低（组内 Hedges 的g =.72–1.02），RCT 结果显示在 3 个月的随访中保持收益。RCT 中的 WLC 组也显着改善，但研究 1 的功效不足，有利于 iCBT 的中等组间效应未达到显着性（g =0.64；95% CI，–0.10–1.38）。

当提供最少的临床医生指导时，这项研究为 iCBT 对 PTSD 的效用提供了初步支持。未来的研究需要阐明不同水平的临床医生支持对 PTSD iCBT 结果的影响，以及探索如何最好地将 iCBT 整合到大规模的 PTSD 常规临床护理中。