Astrocytes are brain cells that react to Alzheimer’s disease pathology in ways that can have either beneficial or detrimental effects. In this issue of Cell Metabolism, Ju et al. outline a novel strategy for coercing astrocytes to a neuroprotective state by maintaining liver-like detoxification in the brain without producing damaging byproducts.

中文翻译：

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利用尿素循环将星形胶质细胞从对阿尔茨海默病的有害转变为有益

星形胶质细胞是对阿尔茨海默病病理学做出反应的脑细胞，其反应方式可能会产生有益或有害的影响。在本期《细胞代谢》中，Ju 等人。概述了一种通过维持大脑中的肝脏样解毒而不产生破坏性副产物来强制星形胶质细胞进入神经保护状态的新策略。