Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an important complication in a substantial number of critically ill, hospitalized patients with COVID-19. Three groups of fungal pathogens cause co-infections in COVID-19: Aspergillus, Mucorales and Candida species, including Candida auris. Here we review the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries. By evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, we set the scene for future research and development of clinical guidance.

与冠状病毒病 2019 (COVID-19) 相关的侵袭性真菌感染是大量 COVID-19 重症住院患者的重要并发症。三组真菌病原体引起 COVID-19 的共感染：曲霉属、毛霉属和念珠菌属，包括耳念珠菌。在这里，我们回顾了低收入、中等收入和高收入国家由这些真菌引起的 COVID-19 相关侵袭性真菌感染的发生率。通过评估流行病学、临床危险因素、宿主环境的易感性特征以及这些共同感染发病机制的免疫机制，我们为未来临床指导的研究和开发奠定了基础。