ABC portal (http://abc.sklehabc.com) is a database and web portal containing 198 single-cell transcriptomic datasets of development, differentiation and disorder of blood/immune cells. All the datasets were re-annotated with a manually curated and unified single-cell reference, especially for the haematopoietic stem and progenitor cells. ABC portal provides web-based interactive analysis modules, especially a comprehensive cell-cell communication analysis and disease-related gene signature analysis. Importantly, ABC portal allows customized sample selection based on a combination of several metadata for downstream analysis and comparison analysis across datasets. ABC portal also allows users to select multiple cell types for analysis in the modules. Together, ABC portal provides an interactive interface of single-cell data exploration and re-analysis with customized analysis modules for the researchers and clinicians, and will facilitate understanding of haematopoiesis and blood/immune disorders.

中文翻译：

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ABC 门户：血细胞的单细胞数据库和 Web 服务器

ABC 门户 (http://abc.sklehabc.com) 是一个数据库和门户网站，包含 198 个关于血液/免疫细胞发育、分化和紊乱的单细胞转录组数据集。所有数据集都使用手动策划和统一的单细胞参考重新注释，特别是对于造血干细胞和祖细胞。ABC 门户提供基于网络的交互式分析模块，尤其是全面的细胞间通讯分析和疾病相关基因特征分析。重要的是，ABC 门户允许基于多个元数据的组合定制样本选择，以进行下游分析和跨数据集的比较分析。ABC 门户还允许用户在模块中选择多种细胞类型进行分析。一起，