当前位置: X-MOL 学术Nat. Chem. Biol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Voyage to minimal base editors
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2022-08-01 , DOI: 10.1038/s41589-022-01101-8
Beomjong Song 1 , Sangsu Bae 2, 3
Affiliation  

Transposon-associated transposase B (TnpB) is the putative ancestor of Cas nucleases. A TnpB-based adenine base editor has now been developed that is small enough to be loaded into a single AAV vector without compromising editing activity.

中文翻译:

极简碱基编辑之旅

转座子相关转座酶 B (TnpB) 是 Cas 核酸酶的假定祖先。现在已经开发出基于 TnpB 的腺嘌呤碱基编辑器,它足够小,可以加载到单个 AAV 载体中,而不会影响编辑活动。
更新日期:2022-08-02
down
wechat
bug