To explore the relationship between binocular imbalance (BI) and the abnormal development of binocular refraction. BI data were collected by enrolling the first 1,000 adolescents and children aged 6–18 years in Shenzhen Eye Hospital from April 2020 to January 2021. In this cross-sectional study, the imbalance value (IV) did not show a statistical correlation with the spherical equivalent (SE) (oculus dexter [OD]: r = 0.022, p = 0.586; oculus sinister [OS]: r = −0.021, p = 0.606), and had little correlation with the uncorrected visual acuity (VA) (OD: r = −0.084, p = 0.039; OS: r = −0.034, p = 0.408). The proportion of binocular contrast imbalance (BCI) (the absolute value) maintained the highest level (from 54.42 to 79.17 percent) with the increase of bilateral SE difference in the four subcategories (binocular balance, monocular suppression, binocular rivalry, and BCI). From −100 to +100 of IV, the SE of the left eye tends to increase negatively when compared with the right eye (from −95 < IV ≦ −80, SE difference = −0.83 ± 1.58, to −20 < IV ≦ −10, SE difference = −0.14 ± 0.61; from 10 ≦ IV <20, SE difference = −0.05 ± 0.80, to 80 ≦ IV <95, SE difference = 1.48 ± 2.77). BI widely exists within the general pediatric population. The BI did not show significant correlation with the unilateral eye refractive state and the VA. However, the BI may be accompanied by imbalanced development of the eye refractive system. Furthermore, the SE of the dominant eye (from the prospective of BI) tends to be more negative than that of the opposite eye as the value increases.

中文翻译：

---

探索双眼不平衡与近视的关系：使用虚拟现实平台进行折射

探讨双眼不平衡（BI）与双眼屈光异常发展的关系。BI 数据是通过 2020 年 4 月至 2021 年 1 月在深圳眼科医院招收的首批 1000 名 6-18 岁青少年和儿童收集的。在这项横断面研究中，不平衡值 (IV) 与球面值没有显示出统计相关性。等效 (SE) (oculus dexter [OD]: r  = 0.022, p  = 0.586; oculus sinister [OS]: r  = -0.021, p  = 0.606)，并且与未矫正视力 (VA) (OD: r  = -0.084，p  = 0.039；OS：r  = -0.034，p = 0.408）。随着4个亚类（双眼平衡、单眼抑制、双眼竞争和BCI）双侧SE差异的增加，双眼对比度不平衡（BCI）的比例（绝对值）保持最高水平（从54.42%到79.17%）。从 IV 的 -100 到 +100，与右眼相比，左眼的 SE 趋于负增加（从 -95 < IV ≦ -80，SE 差异 = -0.83 ± 1.58，到 -20 < IV ≦ - 10，SE 差异 = -0.14 ± 0.61；从 10 ≦ IV <20，SE 差异 = -0.05 ± 0.80，到 80 ≦ IV <95，SE 差异 = 1.48 ± 2.77)。BI 广泛存在于普通儿科人群中。BI与单侧眼屈光状态和VA无显着相关性。然而，BI可能伴随眼屈光系统的不平衡发育。