Sinonasal malignancies make up <5% of all head and neck neoplasms, with an incidence of 0.5–1.0 per 100,000. The outcome of these rare malignancies has been poor, whereas significant progress has been made in the management of other cancers. The objective of the current review was to describe the incidence, causes, presentation, diagnosis, treatment, and recent developments of malignancies of the sinonasal tract. The diagnoses covered in this review included sinonasal undifferentiated carcinoma, sinonasal adenocarcinoma, sinonasal squamous cell carcinoma, and esthesioneuroblastoma, which are exclusive to the sinonasal tract. In addition, the authors covered malignances that are likely to be encountered in the sinonasal tract—primary mucosal melanoma, NUT (nuclear protein of the testis) carcinoma, and extranodal natural killer cell/T-cell lymphoma. For the purpose of keeping this review as concise and focused as possible, sarcomas and malignancies that can be classified as salivary gland neoplasms were excluded.

中文翻译：

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成人鼻窦癌的当代治疗


鼻窦恶性肿瘤占所有头颈部肿瘤的比例<5%，发病率为每 10 万人中 0.5-1.0 例。这些罕见恶性肿瘤的治疗效果不佳，而其他癌症的治疗却取得了重大进展。本综述的目的是描述鼻窦恶性肿瘤的发病率、原因、表现、诊断、治疗和最新进展。本综述涵盖的诊断包括鼻腔未分化癌、鼻腔腺癌、鼻腔鳞状细胞癌和视神经母细胞瘤，这些都是鼻腔鼻道特有的疾病。此外，作者还介绍了鼻窦中可能出现的恶性肿瘤——原发性粘膜黑色素瘤、NUT（睾丸核蛋白）癌和结外自然杀伤细胞/T 细胞淋巴瘤。为了使本次综述尽可能简洁和集中，排除了可归类为唾液腺肿瘤的肉瘤和恶性肿瘤。