Hospitalizations for major osteoporotic fractures in Switzerland: a long-term trend analysis between 1998 and 2018,Osteoporosis International

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Hospitalizations for major osteoporotic fractures in Switzerland: a long-term trend analysis between 1998 and 2018
Osteoporosis International ( IF 4.2 ) Pub Date : 2022-08-02 , DOI: 10.1007/s00198-022-06481-0
Kurt Lippuner ₁ , Gergana Rimmer ₁ , Anna K Stuck ₂ , Patrick Schwab ₃ , Oliver Bock ₁

Affiliation

Summary

Between 1998 and 2018, the number of hospitalizations for major osteoporotic fractures increased. After standardization for age, these numerical increases translated into a reduced incidence of hospitalizations for hip fractures and an increased incidence of hospitalizations for spine, proximal humerus, and distal radius fractures in both sexes.

Introduction

The longterm epidemiological trends of hospitalizations for major osteoporotic fractures (MOF) between 1998 and 2018 in Switzerland are unknown.

Methods

The absolute number of acute hospitalizations for MOF (hip fractures and fractures of the spine, proximal humerus, and distal radius) and related length of acute hospital stay were extracted from the medical database of the Swiss Federal Office of Statistics. Age-standardized incidence rates were calculated using 1998 as the reference year.

Results

Hospitalizations for MOF increased from 4483 to 7542 (+ 68.2%) in men and from 13,242 to 19,362 (+ 46.2%) in women. The age-standardized incidence of hospitalizations for MOF increased by 5.7% in men (p = 0.002) and by 5.1% in women (p = 0.018). The age-standardized incidence of hip fractures decreased by 15.3% in men (p < 0.001) and by 21.5% in women (p < 0.001). In parallel, the age-standardized incidence of MOF other than hip fractures increased by 31.8% in men (p < 0.001) and by 40.1% in women (p < 0.001). The mean length of acute hospital stays for MOF decreased from 16.3 to 8.5 days in men and from 16.9 to 8.1 days in women.

Conclusion

Between 1998 and 2018, the number of hospitalizations for MOF increased significantly by a larger extent than expected based on the ageing of the Swiss population alone. This increase was solely driven by an increased incidence of MOF other than hip fractures as incident hip fractures decreased over time in both sexes, more so in women than in men.

中文翻译：

瑞士因严重骨质疏松性骨折住院：1998 年至 2018 年的长期趋势分析

概括

1998 年至 2018 年间，因严重骨质疏松性骨折住院的人数有所增加。在对年龄进行标准化后，这些数字的增加转化为髋部骨折住院率的降低和脊柱、肱骨近端和桡骨远端骨折住院率的增加。

介绍

瑞士 1998 年至 2018 年期间因严重骨质疏松性骨折 (MOF) 住院的长期流行病学趋势尚不清楚。

方法

MOF（髋部骨折和脊柱、肱骨近端和桡骨远端骨折）急性住院的绝对数量和相关的急性住院时间是从瑞士联邦统计局的医学数据库中提取的。年龄标准化发病率是使用 1998 年作为参考年计算的。

结果

男性因 MOF 住院的人数从 4483 人增加到 7542 人（+ 68.2%），女性从 13,242 人增加到 19,362 人（+ 46.2%）。MOF 的年龄标准化住院率在男性中增加了 5.7%（p = 0.002），在女性中增加了 5.1%（p = 0.018）。男性髋部骨折的年龄标准化发病率下降了 15.3%（p < 0.001），女性下降了 21.5%（p < 0.001）。与此同时，除髋部骨折以外的年龄标准化 MOF 发病率在男性中增加了 31.8%（p < 0.001），在女性中增加了 40.1%（p < 0.001）。MOF 的平均急性住院时间男性从 16.3 天减少到 8.5 天，女性从 16.9 天减少到 8.1 天。