FeCl3-Catalyzed Synthesis of Tanshinlactone Analogues from 1H-Indene-1,2,3-triones and Alkynes,The Journal of Organic Chemistry

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FeCl3-Catalyzed Synthesis of Tanshinlactone Analogues from 1H-Indene-1,2,3-triones and Alkynes
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2022-08-01 , DOI: 10.1021/acs.joc.2c01254
Zhenzhu Hu ₁ , Peng Ma ₁ , Ning Ma ₁ , Jianhui Wang _{1,

2}

Affiliation

Tanshinlactone has been found in several natural products and biologically active compounds. Herein, a new FeCl₃-catalyzed strategy using 1H-indene-1,2,3-triones and alkynes as starting materials is reported to obtain various tanshinlactone derivatives. This protocol has the advantages of involving low cost, environmentally benign catalysts, simple reaction conditions, and a broad range of substrates.

中文翻译：

FeCl3-催化1H-茚-1,2,3-三酮和炔烃合成丹参内酯类似物

在几种天然产物和生物活性化合物中发现了丹参内酯。本文报道了一种新的 FeCl ₃催化策略，使用 1 H-茚-1,2,3-三酮和炔烃作为起始原料，以获得各种丹参内酯衍生物。该协议具有成本低、对环境友好的催化剂、简单的反应条件和广泛的底物等优点。

更新日期：2022-08-01

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