Two recent randomized trials provide evidence to guide the management of sepsis. The CLASSIC trial reports that restrictive fluid therapy has no mortality benefit compared to a standard regimen in patients with septic shock, whereas the LOVIT trial reports that high-dose intravenous vitamin C might be harmful in patients with severe sepsis.

中文翻译：

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脓毒症的限制性液体疗法和大剂量维生素 C


最近的两项随机试验为指导脓毒症的治疗提供了证据。 CLASSIC 试验报告称，与标准治疗方案相比，限制性液体治疗对于脓毒症休克患者没有死亡率益处，而 LOVIT 试验报告称，高剂量静脉注射维生素 C 对于严重脓毒症患者可能有害。