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Intraparenchymal brain hemorrhage due to rupture of aneurysm in infants: report of two cases
Egyptian Pediatric Association Gazette ( IF 0.5 ) Pub Date : 2022-08-01 , DOI: 10.1186/s43054-022-00111-4
Yolanda Rubio Atienza , Emilio Ibiza Palacios , Maria Pilar del Peral Samaniego , Pablo Álvarez Montañana , Maria Molina Corbacho , Vicent Modesto i Alapont

Cerebral or brain hemorrhage due to the rupture of intracranial aneurysms is extremely rare in pediatric population. The aim of our work is to describe two cases in children and to review the existent bibliography about this issue. Both of our patients presented with nonspecific symptoms and subsequent neurological deficit. The brain imaging test revealed intraparenchymal hemorrhage. In both cases, the aneurysm was located at the distal portion of the middle cerebral artery. Surgical intervention was needed, clipping the aneurysm due to the impossibility of intravascular embolization. After the surgery, one patient presented with persistent hydrocephalus secondary to intraventricular hemorrhage, requiring the placement of a cerebrospinal fluid shunt. Over time, the child presented with refractory epilepsy compatible with West syndrome. The second patient did not present postoperative complications but died suddenly 2 months after. Our two patients presented with a middle cerebral artery aneurysm at the distal level, which seems to be the most frequent location according to literature. The correct diagnosis can be delayed because of the nonspecific initial symptoms, as occurred in one of our patients with a delay of 3 days from the onset of symptoms. In both patients, surgical treatment was preferred over endovascular treatment, due to the anatomical characteristics of the aneurysm and the patient’s age. Torpid evolution is also described, with one of our patients dying at 2 months, probably due to rebleeding, and the other suffering right hemiparesis and epilepsy compatible with West syndrome.

中文翻译:

婴儿动脉瘤破裂致脑实质内出血2例报告

由于颅内动脉瘤破裂导致的脑或脑出血在儿科人群中极为罕见。我们工作的目的是描述两个儿童案例,并回顾关于这个问题的现有参考书目。我们的两名患者都出现了非特异性症状和随后的神经功能缺损。脑成像测试显示脑实质内出血。在这两种情况下,动脉瘤都位于大脑中动脉的远端。由于不可能进行血管内栓塞,因此需要手术干预,夹住动脉瘤。手术后,一名患者出现继发于脑室内出血的持续性脑积水,需要置入脑脊液分流管。随着时间的推移,孩子出现了符合 West 综合征的难治性癫痫。第二名患者没有出现术后并发症,但在 2 个月后突然死亡。我们的两名患者在远端水平出现大脑中动脉瘤,根据文献,这似乎是最常见的位置。由于非特异性的初始症状,正确的诊断可能会延迟,正如我们的一名患者在症状出现后延迟 3 天时发生的那样。由于动脉瘤的解剖特征和患者的年龄,在这两名患者中,手术治疗优于血管内治疗。还描述了缓慢的进化,我们的一名患者在 2 个月时死亡,可能是由于再出血,另一名患者患有与 West 综合征相符的右侧偏瘫和癫痫。我们的两名患者在远端水平出现大脑中动脉瘤,根据文献,这似乎是最常见的位置。由于非特异性的初始症状,正确的诊断可能会延迟,正如我们的一名患者在症状出现后延迟 3 天时发生的那样。由于动脉瘤的解剖特征和患者的年龄,在这两名患者中,手术治疗优于血管内治疗。还描述了缓慢的进化,我们的一名患者在 2 个月时死亡,可能是由于再出血,另一名患者患有与 West 综合征相符的右侧偏瘫和癫痫。我们的两名患者在远端水平出现大脑中动脉瘤,根据文献,这似乎是最常见的位置。由于非特异性的初始症状,正确的诊断可能会延迟,正如我们的一名患者在症状出现后延迟 3 天时发生的那样。由于动脉瘤的解剖特征和患者的年龄,在这两名患者中,手术治疗优于血管内治疗。还描述了缓慢的进化,我们的一名患者在 2 个月时死亡,可能是由于再出血,另一名患者患有与 West 综合征相符的右侧偏瘫和癫痫。由于非特异性的初始症状,正确的诊断可能会延迟,正如我们的一名患者在症状出现后延迟 3 天时发生的那样。由于动脉瘤的解剖特征和患者的年龄,在这两名患者中,手术治疗优于血管内治疗。还描述了缓慢的进化,我们的一名患者在 2 个月时死亡,可能是由于再出血,另一名患者患有与 West 综合征相符的右侧偏瘫和癫痫。由于非特异性的初始症状,正确的诊断可能会延迟,正如我们的一名患者在症状出现后延迟 3 天时发生的那样。由于动脉瘤的解剖特征和患者的年龄,在这两名患者中,手术治疗优于血管内治疗。还描述了缓慢的进化,我们的一名患者在 2 个月时死亡,可能是由于再出血,另一名患者患有与 West 综合征相符的右侧偏瘫和癫痫。
更新日期:2022-08-01
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