Copper doped zinc oxide nanoparticles (Cu-ZnO Nps) are known to be one of the multifunctional inorganic materials with effective antibacterial activity. In the present study, un-doped and copper doped zinc oxide with varying concentration i.e., Zn1-x CuxO (where x = 0, 0.01, 0.02 and 0.03%) have been synthesized via microwave assisted method and characterized by XRD, SEM, EDAX, TEM, UV-VIS-DRS spectroscopy. X-ray diffraction studies show that the Cu-ZnO Nps exhibit hexagonal wurtzite structure and the particle size are found to be within the range between 20 to 35 nm. Cu-ZnO Nps exhibit appreciable catalytic activity (89.9% yields) in the transformation of benzylalcohol to benzaldehyde. Significant antibacterial activity is shown by Cu-ZnO Nps against bacterial strains such as E. coli, S. aureus, Klebsiella and B. subtilis with zone of inhibition of 15 ± 0.08, 17 ± 0.21, 21 ± 0.01 and 23 ± 0.69 mm respectively in contrast to standard antibiotic streptomycin. The in vitro cytotoxicity of ZnO and Cu-ZnO Nps has been determined against human breast (MCF7) and human cervical (HeLa) cancer cell lines using MTT assay.

中文翻译：

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微波辅助法合成 Cu 掺杂 ZnO 纳米粒子的催化和生物活性增强

铜掺杂氧化锌纳米粒子（Cu-ZnO Nps）是一种具有有效抗菌活性的多功能无机材料。在本研究中，通过微波辅助方法合成了不同浓度的未掺杂和铜掺杂氧化锌，即 Zn1-x CuxO（其中 x = 0、0.01、0.02 和 0.03%），并通过 XRD、SEM、EDAX 进行了表征。 、TEM、UV-VIS-DRS 光谱。X 射线衍射研究表明，Cu-ZnO Nps 呈现出六方纤锌矿结构，粒径在 20 至 35 nm 之间。Cu-ZnO Nps 在苯甲醇转化为苯甲醛的过程中表现出明显的催化活性（产率 89.9%）。Cu-ZnO Nps 对大肠杆菌、金黄色葡萄球菌、克雷伯氏菌和 B 等细菌菌株具有显着的抗菌活性。与标准抗生素链霉素相比，枯草芽孢杆菌的抑制区分别为 15 ± 0.08、17 ± 0.21、21 ± 0.01 和 23 ± 0.69 mm。已使用 MTT 测定法确定了 ZnO 和 Cu-ZnO Nps 对人乳腺癌 (MCF7) 和人宫颈 (HeLa) 癌细胞系的体外细胞毒性。