In the present study, a 3D coordination polymer with the chemical composition of[(CH3)2NH2][Ca(tcpbH)(H2O)] (1) has been solvothermally obtained from a rigid tetracarboxylic acid ligand tetrakis-(4-carboxyphenyl)benzene (H4tcpb) and alkaline-earth ion CaII. Complex 1 has been well studied via Fourier-transform infrared spectroscopy, elemental analysis (EA), TG analysis and single-crystal X-ray diffraction analysis. Its application values on the childhood asthma were determined and the internal principle has been discussed simultaneously. Firstly, the ELISA is utilized to measure the content of inflammatory cytokines released into the Broncho alveolar lavage fluid (BALF) after compound treatment. In addition to this, the real time RT-PCR was conducted to measure the relative expression levels of NF-κB signaling pathway in the alveolar epithelial cells.

中文翻译：

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一种新的 Ca(II) 配位聚合物：儿童哮喘的结构表征和治疗活性

在本研究中，化学成分为[(CH3)2NH2][Ca(tcpbH)(H2O)] (1) 的 3D 配位聚合物已从刚性四羧酸配体四-(4-羧基苯基)苯溶剂热法制得。 (H4tcpb) 和碱土离子 CaII。配合物 1 已通过傅里叶变换红外光谱、元素分析 (EA)、TG 分析和单晶 X 射线衍射分析得到很好的研究。确定了其在儿童哮喘中的应用价值，同时讨论了其内在原理。首先，利用ELISA测定复方处理后释放到支气管肺泡灌洗液（BALF）中的炎性细胞因子的含量。除此之外，