Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak,Lab on a Chip

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Selection and characterisation of bioreceptors to develop nanoparticle-based lateral-flow immunoassays in the context of the SARS-CoV-2 outbreak
Lab on a Chip ( IF 6.1 ) Pub Date : 2022-07-29 , DOI: 10.1039/d2lc00486k
Liming Hu ₁ , Enric Calucho ₁ , Celia Fuentes-Chust ₁ , Claudio Parolo _{1,

2} , Andrea Idili ₁ , Ruslan Álvarez-Diduk ₁ , Lourdes Rivas ₁ , Arben Merkoçi _{1,

3}

Affiliation

This manuscript aims at raising the attention of the scientific community to the need for better characterised bioreceptors for fast development of point-of-care diagnostic devices able to support mass frequency testing. Particularly, we present the difficulties encountered in finding suitable antibodies for the development of a lateral flow assay for detecting the nucleoprotein of SARS-CoV-2.

中文翻译：

在 SARS-CoV-2 爆发的背景下选择和表征生物受体以开发基于纳米颗粒的横向流动免疫测定

这份手稿旨在提高科学界对更好表征生物受体的需求，以便快速开发能够支持大规模频率测试的即时诊断设备。特别是，我们提出了在寻找合适的抗体以开发用于检测 SARS-CoV-2 核蛋白的侧流测定法时遇到的困难。

更新日期：2022-07-29

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