In this review, we discuss gas phase experimentation centered on the measurement of acidity and proton affinity of substrates that are useful for understanding catalytic mechanisms. The review is divided into two parts. The first covers examples of organocatalysis, while the second focuses on biological catalysis. The utility of gas phase acidity and basicity values for lending insight into mechanisms of catalysis is highlighted.

中文翻译：

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有机和生物有机催化中的质谱分析：利用热化学性质深入了解机理

在这篇综述中，我们讨论了以测量底物的酸度和质子亲和力为中心的气相实验，这有助于理解催化机制。审查分为两部分。第一个涵盖有机催化的例子，第二个则重点关注生物催化。强调了气相酸度和碱度值对于深入了解催化机制的效用。