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Insulin sensitive human adipocytes for in vitro studies
Nature Reviews Endocrinology ( IF 40.5 ) Pub Date : 2022-07-27 , DOI: 10.1038/s41574-022-00727-x
Leon G Straub 1 , Philipp E Scherer 1, 2
Affiliation  

Adipocyte insulin resistance is a driving force for systemic insulin resistance. Advances in human stem cell culture have established conditions for human adipocytes that give rise to a reproducible population of adipocytes that retain a high level of insulin sensitivity, paving the way for high throughput screening approaches.

中文翻译:

用于体外研究的胰岛素敏感性人体脂肪细胞

脂肪细胞胰岛素抵抗是系统性胰岛素抵抗的驱动力。人类干细胞培养的进步为人类脂肪细胞建立了条件,从而产生了可重复的脂肪细胞群,这些脂肪细胞保持了高水平的胰岛素敏感性,为高通量筛选方法铺平了道路。
更新日期:2022-07-28
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