Adolescents with overweight/obesity are at risk for vitamin D insufficiency and deficiency. Both overweight/obesity and vitamin D insufficiency/deficiency may predispose to fractures. We enrolled 103 participants (53.3% females, 15.9 ± 2.2 years) in a retrospective case-control study to determine whether an association exists between fractures and a low 25-hydroxyvitamin D (25[OH]D) among adolescents whose body mass index (BMI) ≥ 85 percentile. Cases (n = 28) sustaining a low/medium impact fracture were matched to controls (n = 75) without a fracture history. A conditional-logistic regression analysis addressing the common vitamin D insufficiency/deficiency cutoffs was used. Overweight, obesity, and significant obesity rates were 10.7%, 53.4%, and 35.9%, respectively. Mean (±SD) 25(OH)D was 16.5 ± 6.4 ng/mL. In all, 25(OH)D insufficiency rates (level <20 ng/mL) were 70.5%. Matched cases and controls had similar 25(OH)D insufficiency/deficiency rates (P > .05). Controlling for race and seasonality showed no association between fractures and 25(OH)D insufficiency/deficiency (P > .05). These data suggest that fractures are not associated with low 25(OH)D levels among adolescents whose BMI ≥ 85th percentile.

超重/肥胖的青少年面临维生素 D 不足和缺乏的风险。超重/肥胖和维生素 D 不足/缺乏都可能导致骨折。我们在一项回顾性病例对照研究中招募了 103 名参与者（53.3% 为女性，15.9 ± 2.2 岁），以确定在体重指数为 ( BMI) ≥ 85 个百分点。发生低/中度冲击性骨折的病例 (n = 28) 与没有骨折史的对照组 (n = 75) 相匹配。使用了解决常见维生素 D 不足/缺乏临界值的条件逻辑回归分析。超重、肥胖和显着肥胖率分别为10.7%、53.4%和35.9%。平均 (±SD) 25(OH)D 为 16.5 ± 6.4 ng/mL。在所有，25(OH)D 不足率（水平 <20 ng/mL）为 70.5%。匹配的病例和对照具有相似的 25(OH)D 不足/缺乏率（P > .05）。控制种族和季节性因素显示骨折与 25(OH)D 不足/缺乏之间没有关联 ( P > .05)。这些数据表明，在 BMI ≥ 85% 的青少年中，骨折与低 25(OH)D 水平无关。