AIMing 2 treat atherosclerosis,Nature Reviews Cardiology

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AIMing 2 treat atherosclerosis
Nature Reviews Cardiology ( IF 41.7 ) Pub Date : 2022-07-26 , DOI: 10.1038/s41569-022-00755-0
Oliver Soehnlein _{1,

2} , Alan R Tall ₃

Affiliation

The AIM2 inflammasome is activated by host and pathogen DNA. Work from the past 5 years indicates that the AIM2 inflammasome has an important role in advanced atherosclerosis driven by clonal haematopoiesis and possibly in atherosclerosis accelerated by acute infection. Therefore, the AIM2 inflammasome might be an important target for precision medicine.

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