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Bioprosthetic Aortic Valve Hemodynamics: Definitions, Outcomes, and Evidence Gaps
Journal of the American College of Cardiology ( IF 21.7 ) Pub Date : 2022-07-25 , DOI: 10.1016/j.jacc.2022.06.001
Howard C Herrmann 1 , Philippe Pibarot 2 , Changfu Wu 3 , Rebecca T Hahn 4 , Gilbert H L Tang 5 , Amr E Abbas 6 , David Playford 7 , Marc Ruel 8 , Hasan Jilaihawi 9 , Janarthanan Sathananthan 10 , David A Wood 10 , Ruggero De Paulis 11 , Jeroen J Bax 12 , Josep Rodes-Cabau 2 , Duke E Cameron 13 , Tiffany Chen 1 , Pedro J Del Nido 14 , Marc R Dweck 15 , Tsuyoshi Kaneko 16 , Azeem Latib 17 , Neil Moat 18 , Thomas Modine 19 , Jeffrey J Popma 20 , Jamie Raben 3 , Robert L Smith 21 , Didier Tchetche 22 , Martyn R Thomas 23 , Flavien Vincent 24 , Ajit Yoganathan 25 , Bram Zuckerman 3 , Michael J Mack 21 , Martin B Leon 4 ,
Affiliation  

A virtual workshop was organized by the Heart Valve Collaboratory to identify areas of expert consensus, areas of disagreement, and evidence gaps related to bioprosthetic aortic valve hemodynamics. Impaired functional performance of bioprosthetic aortic valve replacement is associated with adverse patient outcomes; however, this assessment is complicated by the lack of standardization for labelling, definitions, and measurement techniques, both after surgical and transcatheter valve replacement. Echocardiography remains the standard assessment methodology because of its ease of performance, widespread availability, ability to do serial measurements over time, and correlation with outcomes. Management of a high gradient after replacement requires integration of the patient’s clinical status, physical examination, and multimodality imaging in addition to shared patient decisions regarding treatment options. Future priorities that are underway include efforts to standardize prosthesis sizing and labelling for both surgical and transcatheter valves as well as trials to characterize the consequences of adverse hemodynamics.



中文翻译:

生物主动脉瓣血流动力学:定义、结果和证据缺口

Heart Valve Collaboratory 组织了一次虚拟研讨会,以确定与生物假体主动脉瓣血流动力学相关的专家共识领域、分歧领域和证据缺口。生物主动脉瓣置换术功能受损与不良患者预后相关;然而,由于在手术和经导管瓣膜置换术后缺乏标签、定义和测量技术的标准化,这种评估变得复杂。超声心动图仍然是标准的评估方法,因为它易于执行、广泛可用、能够随时间进行连续测量,并且与结果相关。置换后高梯度的管理需要综合患者的临床状况、体格检查、和多模态成像,以及关于治疗方案的共同患者决定。正在进行的未来优先事项包括努力使外科和经导管瓣膜的假体尺寸和标签标准化,以及进行表征不利血液动力学后果的试验。

更新日期:2022-07-25
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