Bioprosthetic valve dysfunction (BVD) and bioprosthetic valve failure (BVF) may be caused by structural or nonstructural valve dysfunction. Both surgical and transcatheter bioprosthetic valves have limited durability because of structural valve deterioration. The main objective of this summary of experts participating in a virtual workshop was to propose standardized definitions for nonstructural and structural BVD and BVF following aortic or mitral biological valve replacement with the goal of facilitating research reporting and implementation of these terms in clinical practice. Definitions of structural BVF, based on valve reintervention or death, underestimate the true incidence of BVF. However, definitions solely based on the presence of high transprosthetic gradient at a given echocardiogram during follow-up overestimate the incidence of structural BVD and BVF. Definitions of aortic or mitral structural BVD must therefore include the confirmation by imaging of permanent structural changes to the leaflets alongside evidence of deterioration in valve hemodynamic function at echocardiography follow-up.

生物瓣膜功能障碍 (BVD) 和生物瓣膜衰竭 (BVF) 可能由结构性或非结构性瓣膜功能障碍引起。由于瓣膜结构退化，外科瓣膜和经导管生物瓣膜的耐用性都有限。参加虚拟研讨会的专家总结的主要目的是为主动脉或二尖瓣生物瓣置换术后的非结构性和结构性 BVD 和 BVF 提出标准化定义，目的是促进研究报告和这些术语在临床实践中的实施。基于瓣膜再介入或死亡的结构性 BVF 定义低估了 BVF 的真实发生率。然而，仅基于随访期间给定超声心动图中存在高经假体梯度的定义高估了结构性 BVD 和 BVF 的发生率。因此，主动脉或二尖瓣结构性 BVD 的定义必须包括通过影像学确认瓣叶的永久性结构变化以及超声心动图随访中瓣膜血流动力学功能恶化的证据。