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A microfluidic droplet system for ultra-monodisperse droplet generation: A universal approach
Chemical Engineering Science ( IF 4.1 ) Pub Date : 2022-07-22 , DOI: 10.1016/j.ces.2022.117947
Ali Kalantarifard , Elnaz Alizadeh-Haghighi , Caglar Elbuken

Despite the importance of droplet monodispersity, a universal methodology for high monodispersity droplet generation does not exist yet. We have recently demonstrated that unlike the conventional method of droplet generation, applying an identical pressure from a single source makes the microfluidic droplet system immune to the external fluctuations that originate from the imperfection of the flow source. In this work, we show that our method is universal and applicable to other common microfluidic devices and flow sources. We applied this method to flow-focusing and coflow devices that are commonly used for high-frequency microdroplet generation. In addition to the pressure pump, we used a syringe pump to show that our method is applicable to flow rate controllable systems as well. We compared the monodispersity of droplets formed by the conventional methods and the novel method explained in this work.



中文翻译:

用于超单分散液滴生成的微流体液滴系统:一种通用方法

尽管液滴单分散性很重要,但尚不存在用于产生高单分散性液滴的通用方法。我们最近证明,与传统的液滴生成方法不同,从单一来源施加相同的压力可以使微流控液滴系统免受源自流源缺陷的外部波动的影响。在这项工作中,我们表明我们的方法是通用的,适用于其他常见的微流体装置和流源。我们将此方法应用于通常用于高频微滴生成的流动聚焦和协同流动装置。除了压力泵,我们还使用了注射泵来证明我们的方法也适用于流量可控系统。

更新日期:2022-07-22
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