Compound Interaction Screen on a Photoactivatable Cellulose Membrane (CISCM) Identifies Drug Targets,ChemMedChem

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Compound Interaction Screen on a Photoactivatable Cellulose Membrane (CISCM) Identifies Drug Targets
ChemMedChem ( IF 3.6 ) Pub Date : 2022-07-22 , DOI: 10.1002/cmdc.202200346
F Teresa I Melder ₁ , Peter Lindemann ₂ , Alexander Welle ₃ , Vanessa Trouillet ₄ , Stefan Heißler ₃ , Marc Nazaré ₂ , Matthias Selbach ₁

Affiliation

Parallel identification: We present a new compound interaction screen on a cellulose membrane (CISCM) that combines undirected photoimmobilization of compounds on cellulose with affinity purification mass spectrometry and label free quantification (LFQ) to identify the protein targets of several compounds in parallel.

中文翻译：