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Human Biomonitoring of Polychlorinated Biphenyls (PCBs) in the Breast Milk of Colombian Mothers
Bulletin of Environmental Contamination and Toxicology ( IF 2.7 ) Pub Date : 2022-07-22 , DOI: 10.1007/s00128-022-03577-5
Boris Santiago Avila 1, 2 , Carolina Ramírez 1 , Eliana Tellez-Ávila 1
Affiliation  

Polychlorinated biphenyls (PCBs) are persistent in the environment, bioaccumulate and biomagnify throughout the food chain, and may have adverse effects on human health and wildlife. PCB indicator (PCB 28, PCB 52, PCB 101, PCB 118, PCB 138, PCB 153, and PCB 180) were monitored in human milk using 68 samples from healthy and primiparous mothers from seven cities in Colombia, and the estimated daily intake (EDI) of infants was calculated. The PCB indicator with the highest concentration was PCB 153 with a value of 7.30 ng g−1 lipids. The maximum EDI was calculated as 0.257 μg kg−1 bw−1 day−1. In general, the PCB levels found in the 68 samples were low and did not represent a risk to breastfed infants. Additionally, these results could strengthen Colombia’s efforts to increase the practice of breastfeeding. Finally, the results establish a general overview of population exposure and can be a scientific tool to improve environmental health policies in the country.



中文翻译:

哥伦比亚母亲母乳中多氯联苯 (PCBs) 的人体生物监测

多氯联苯 (PCB) 在环境中持久存在,在整个食物链中具有生物累积和生物放大作用,可能对人类健康和野生动物产生不利影响。使用来自哥伦比亚七个城市的健康和初产母亲的 68 个样本监测母乳中的 PCB 指标(PCB 28、PCB 52、PCB 101、PCB 118、PCB 138、PCB 153 和 PCB 180),估计每日摄入量(计算婴儿的 EDI)。浓度最高的 PCB 指示剂是 PCB 153,其值为 7.30 ng g -1脂质。最大 EDI 计算为 0.257 μg kg -1  bw -1  day -1. 一般来说,在 68 个样本中发现的多氯联苯含量较低,并不代表母乳喂养婴儿的风险。此外,这些结果可以加强哥伦比亚在增加母乳喂养实践方面的努力。最后,结果建立了人口暴露的总体概况,可以作为改进该国环境健康政策的科学工具。

更新日期:2022-07-22
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