Objective

To investigate the correlation between preoperative DVT and the time from injury to surgery (TFITS), and provide a clinical reference for the prevention of preoperative DVT.

Patients and methods

We collected the clinical data of patients with lower extremities fractures between September 1, 2014, and May 31, 2019. Doppler ultrasonography was used to diagnose DVT. Patients were divided into the 0-2d group, 3-4d group, 5-7d group, and >7d group according to TFITS. The correlation between TFITS and preoperative DVT was assessed using logistic regression according to the adjusted model.

Result

A total of 2831 patients were included in the study. The mean（+/-SD） TFITS was 6.11 ± 3.76 (0 to 21 d). A total of 821 (29.0%) cases had preoperative DVT, with the incidence of DVT being 8.0% in the 0-2d group, 23.8% in the 3-4d group, 32.0% in the 5-7d group, and 36.2% in the >7d group, with statistically significant differences(P＜0.05) among all the groups. The incidence of preoperative DVT increased with prolonged preoperative time. In the fully adjusted model, TFITS was positively correlated with the incidence of preoperative DVT (OR: 1.093; 95% CI: 1.068-1.118; P = 0.000), and the strength of the association increased with increasing time.

Conclusion

TFITS was an independent risk factor on the incidence of preoperative DVT. After excluding the effect of other factors, each 1d increases in TFITS was correlated with a 9.3% increase in the risk of preoperative DVT. The TFITS should be decreased to reduce the risk of preoperative DVT.

中文翻译：

---

术前下肢深静脉血栓形成（DVT）与受伤至手术时间（TFITS）的相关性

客观的

探讨术前深静脉血栓形成与受伤至手术时间（TFITS）的相关性，为术前深静脉血栓的预防提供临床参考。

患者和方法

我们收集了 2014 年 9 月 1 日至 2019 年 5 月 31 日期间下肢骨折患者的临床资料。多普勒超声用于诊断 DVT。根据TFITS将患者分为0-2d组、3-4d组、5-7d组和>7d组。根据调整后的模型，使用逻辑回归评估 TFITS 与术前 DVT 之间的相关性。

结果

共有 2831 名患者被纳入研究。平均（+/-SD）TFITS 为 6.11 ± 3.76（0 至 21 d）。术前发生深静脉血栓821例（29.0%），0-2d组发生率8.0%，3-4d组23.8%，5-7d组32.0%，5-7d组36.2%。 >7d组，各组间差异有统计学意义（P＜0.05）。术前深静脉血栓的发生率随着术前时间的延长而增加。在完全调整的模型中，TFITS 与术前 DVT 的发生率呈正相关（OR：1.093；95% CI：1.068-1.118；P = 0.000），并且关联强度随着时间的增加而增加。

结论

TFITS 是术前 DVT 发生率的独立危险因素。排除其他因素的影响后，TFITS 每增加 1 天与术前 DVT 风险增加 9.3% 相关。应降低 TFITS 以降低术前 DVT 的风险。