Tetracycline (TC) has poor degradability and hepatotoxicity which will increase the burden on the aquatic environment when discharged into lakes in large quantities. LDH materials are often used as adsorbents because of their superior surface area and controllability of morphology. Herein, NiFe LDH hollow microspheres (NFHMS) were synthesized by a facile hydrothermal method. The removal of tetracycline by the as-prepared material in an aquatic environment was systematically investigated through comprehensive characterizations. The NFHMS sample presents a larger specific surface area than the two control samples, which contributes to its higher adsorption performance. The adsorption mechanisms of TC on NFHMS is mainly electrostatic adsorption. The fitting results of experimental data coincide well with pseudo-second-order and Weber-Morris models through kinetic simulation. Moreover, the Langmuir model is verified to be more suitable than the Freundlich model in elucidating molecular surface adsorption, and the maximum adsorption capacity of NFHMS obtained from the Langmuir model is 90.9 mg g⁻¹. Higher temperature is beneficial to improve the adsorption performance, and the adsorption process is spontaneous and endothermic. The initial pH of the solution will affect the adsorption capacity, and the partial neutral condition is more favorable. In addition, NFHMS sample exhibits good stability in cyclic tests. Therefore, NFHMS material is expected to be a very promising adsorbent for treating tetracycline in wastewater.

四环素（TC）降解性差，具有肝毒性，大量排入湖泊会增加水环境的负担。LDH材料由于其优异的表面积和形态可控性而经常被用作吸附剂。在此，通过简便的水热法合成了 NiFe LDH 空心微球 (NFHMS)。通过综合表征系统地研究了所制备材料在水生环境中对四环素的去除。NFHMS 样品比两个对照样品具有更大的比表面积，这有助于其更高的吸附性能。TC在NFHMS上的吸附机理主要是静电吸附。通过动力学模拟，实验数据的拟合结果与伪二级模型和韦伯-莫里斯模型吻合良好。此外，Langmuir 模型被证实比 Freundlich 模型更适用于阐明分子表面吸附，从 Langmuir 模型获得的 NFHMS 的最大吸附容量为 90.9 mg g^-1。较高的温度有利于提高吸附性能，吸附过程是自发吸热的。溶液的初始pH值会影响吸附能力，偏中性条件更为有利。此外，NFHMS 样品在循环测试中表现出良好的稳定性。因此，NFHMS材料有望成为一种非常有前景的用于处理废水中四环素的吸附剂。