Online monitoring of organic micropollutants (OMPs) in the aquatic environment at high temporal resolution is an upcoming technique that provides insights into their dynamics and has the potential to bring water research and management to a new level. An online monitoring setup was developed to quantify OMPs in wastewater treatment plant (WWTP) influent and effluent using automated and continuous sampling, sample preparation, online solid-phase extraction-liquid chromatography-tandem mass spectrometry analysis and data evaluation. This online monitoring setup provided high selectivity and sensitivity (limit of quantification down to 1 ng/L) as well as a stable performance during one week of constant operation whilst using a high sampling frequency of 10 min (>1000 samples). Custom automated data evaluation enabled quantification within seconds after each measurement and results were comparable to those from a commercial software. Additionally, an alarm tool was included in the evaluation application, which automatically notified the user in case a substance exceeded a predefined threshold. The online monitoring setup was applied to WWTP influent and effluent, where 57 substances were monitored over a period of one week and two days, respectively. High temporal resolution enabled the observation of periodic patterns of pharmaceuticals as well as pollution by OMPs originating from point and diffuse sources, while dynamics of OMPs in WWTP effluent were less pronounced. These new insights into the dynamics of OMPs in WWTP influent, which would not be observable using 24 h composite samples, will be a starting point for new stormwater and wastewater research and management strategies.

以高时间分辨率在线监测水生环境中的有机微污染物 (OMP) 是一项即将推出的技术，可以深入了解其动态，并有可能将水研究和管理提升到一个新的水平。开发了一种在线监测装置，使用自动和连续采样、样品制备、在线固相萃取-液相色谱-串联质谱分析和数据评估来量化污水处理厂 (WWTP) 进水和出水中的 OMP。这种在线监测设置提供了高选择性和灵敏度（定量限低至 1 ng/L）以及在一周的恒定操作期间的稳定性能，同时使用 10 分钟的高采样频率（>1000 个样本）。自定义自动数据评估可在每次测量后数秒内进行量化，结果与商业软件的结果相当。此外，评估应用程序中包含一个警报工具，如果物质超过预定义的阈值，它会自动通知用户。在线监测设置应用于污水处理厂的进水和出水，分别在一周和两天的时间内监测了 57 种物质。高时间分辨率能够观察药物的周期性模式以及源自点源和扩散源的 OMP 污染，而 WWTP 流出物中 OMP 的动态不太明显。这些对污水处理厂进水 OMP 动力学的新见解，使用 24 小时复合样品是无法观察到的，