Aims To investigate the effect of subfoveal fluid height (SFFH) on visual outcome after macula-off retinal detachment (RD) repair. Methods Prospective interventional case series of consecutive patients undergoing pars plana vitrectomy with gas tamponade (PPV) for primary macula-off RD with duration of symptomatic loss of central vision (LCV) of ≤1 week. Preoperative SFFH was measured on two occasions an hour apart using optical coherence tomography (OCT) by two independent observers. Postoperative best corrected visual acuity (BCVA) was measured at 3 months. Results Sixty-one patients were included. All patients were pseudophakic after RD repair. The mean preoperative and postoperative BCVA (logarithm of the minimum angle of resolution) at 3 months was 1.41 (±0.71) and 0.15 (±0.12, range 0.00–0.70). Twenty-six patients with SFFH of ≤1500 µm were available for repeat OCT measurements. The variation in SFFH was proportional to the SFFH and showed a logarithmic (base 2) association (r=0.50, p=0.01). Patients were therefore grouped according to their SFFH as group 1: 1–100 µm, group 2: 101–300 µm, group 3: 301–700 µm, group 4: 701–1500 µm and group 5: 1501–3100 µm. BCVA at 3 months significantly reduced with increasing SFFH from 0.04 (±0.03) in group 1 to 0.28 (±0.15) in group 5 (p<0.001) but was not associated with age (p=0.77), preoperative BCVA (p=0.39), duration of LCV (p=0.63) or use of perfluorocarbon liquids (p=0.88). Forty-five patients had SFFH ≤1500 µm and achieved 0.10 (±0.07, range 0.00–0.30) logMAR. Conclusion Visual acuity following PPV for macula-off RD is related to preoperative SFFH regardless of the duration of symptomatic LCV within the first week.

中文翻译：

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黄斑区视网膜脱离中黄斑中心凹下液高度对视力结果的重要性


目的 探讨黄斑脱落性视网膜脱离 (RD) 修复后中心凹下液高度 (SFFH) 对视力结果的影响。方法前瞻性介入病例系列研究连续患者因原发性黄斑脱落 RD 接受平坦部玻璃体切除术联合气体填塞 (PPV)，症状性中心视力丧失 (LCV) 持续时间≤1 周。术前 SFFH 由两名独立观察者使用光学相干断层扫描 (OCT) 每隔一小时测量两次。术后 3 个月测量最佳矫正视力 (BCVA)。结果纳入61名患者。所有患者在 RD 修复后均出现人工晶状体眼。术前和术后 3 个月的平均 BCVA（最小分辨率对数）分别为 1.41 (±0.71) 和 0.15 (±0.12，范围 0.00-0.70)。 26 名 SFFH ≤1500 µm 的患者可进行重复 OCT 测量。 SFFH 的变化与 SFFH 成正比，并显示出对数（以 2 为底）关联（r=0.50，p=0.01）。因此，根据患者的 SFFH 将患者分为第 1 组：1–100 µm、第 2 组：101–300 µm、第 3 组：301–700 µm、第 4 组：701–1500 µm 和第 5 组：1501–3100 µm。随着 SFFH 的增加，3 个月时的 BCVA 显着降低，从第 1 组的 0.04 (±0.03) 降至第 5 组的 0.28 (±0.15) (p<0.001)，但与年龄 (p=0.77)、术前 BCVA (p=0.39) 无关）、LCV 持续时间（p=0.63）或全氟化碳液体的使用（p=0.88）。 45 名患者的 SFFH ≤1500 µm，并达到 0.10（±0.07，范围 0.00–0.30）logMAR。结论 PPV 治疗黄斑脱落 RD 后的视力与术前 SFFH 相关，无论第一周内症状性 LCV 持续时间如何。