Aged people are maintaining many natural teeth due to improved oral health. However, compromised general health and poor oral hygiene habits at earlier ages resulted in poor status of preserved teeth. Therefore, tooth extraction is required in many aged people. More knowledge is needed because there are many risk factors during the surgery in frail aged adults. The aim of this study was to evaluate the cardiovascular response of such a population during tooth extraction and analyze risk factors to provide clinical guidance.

A retrospective study was performed on aged patients with systemic diseases who underwent tooth extraction. Data regarding demographic profiles and cardiovascular parameters of heart rate and blood pressure were collected preoperative, when local anesthesia was administered, at the beginning of tooth extraction, 5 min after tooth extraction, and postoperative. The effects of risk factors, including age, sex, and systemic diseases on these parameters were analyzed with a multilevel model.

Heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) of aged patients increased significantly when performing local anesthesia and tooth extraction. During the operation, the older patients (β = 2.011, P = 0.005) and the diabetics (β = 3.902, P < 0.0001) were associated with higher SBP, while those with more tooth extractions exhibited higher HR (β = 0.893, P = 0.007). Women patients showed both significantly elevated HR (β = 1.687, P < 0.0001) and SBP (β = 2.268, P < 0.0001). However, for coronary artery disease patients, HR (β = −2.747, P < 0.0001) and blood pressure [SBP (β = −4.094, P < 0.0001) and DBP (β = −0.87, P = 0.016)] were markedly lower than those of patients without a diagnosis of coronary artery disease.

Cardiovascular response of aged outpatients with systemic diseases during tooth extraction is quite significant. Age, sex, systemic diseases, and the number of tooth extraction could be risk factors closely associated with cardiovascular response. The findings might provide safety guidance for dentists on tooth extraction in this population.

由于改善了口腔健康，老年人正在保持许多天然牙齿。然而，早期的一般健康状况受损和口腔卫生习惯差，导致牙齿保存状况不佳。因此，许多老年人都需要拔牙。需要更多的知识，因为在体弱的老年人的手术过程中存在许多危险因素。本研究的目的是评估此类人群在拔牙期间的心血管反应，并分析危险因素以提供临床指导。

对接受拔牙的老年全身性疾病患者进行了一项回顾性研究。在术前、局部麻醉时、拔牙开始时、拔牙后 5 分钟和术后收集有关人口统计资料和心率和血压的心血管参数的数据。使用多水平模型分析了包括年龄、性别和全身性疾病在内的风险因素对这些参数的影响。

在进行局部麻醉和拔牙时，老年患者的心率（HR）、收缩压（SBP）和舒张压（DBP）显着增加。术中年龄较大的患者（β=2.011，磷= 0.005) 和糖尿病患者 (β = 3.902,磷< 0.0001) 与更高的 SBP 相关，而那些拔牙次数更多的人则表现出更高的 HR (β = 0.893,磷= 0.007)。女性患者的 HR 均显着升高（β = 1.687，磷< 0.0001) 和 SBP (β = 2.268,磷< 0.0001)。然而，对于冠状动脉疾病患者，HR (β = -2.747,磷< 0.0001) 和血压 [SBP (β = -4.094,磷< 0.0001) 和 DBP (β = -0.87, P= 0.016)] 明显低于未诊断为冠状动脉疾病的患者。

老年全身性疾病门诊患者在拔牙过程中的心血管反应非常显着。年龄、性别、全身性疾病和拔牙次数可能是与心血管反应密切相关的危险因素。该研究结果可能为牙医在该人群中拔牙提供安全指导。