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Framework for multiplicative scaling of single-cell proteomics
Nature Biotechnology ( IF 33.1 ) Pub Date : 2022-07-18 , DOI: 10.1038/s41587-022-01411-1


Many biomedical questions demand scalable, deep, and accurate proteome analysis of small samples, including single cells. A scalable framework of multiplexed data-independent acquisition for mass spectrometry enables time saving by parallel analysis of both peptide ions and protein samples, thereby realizing multiplicative gains in throughput.

中文翻译:

单细胞蛋白质组学乘法缩放框架

许多生物医学问题需要对小样本(包括单细胞)进行可扩展、深入和准确的蛋白质组分析。用于质谱的多路复用数据独立采集的可扩展框架可以通过并行分析肽离子和蛋白质样品来节省时间,从而实现通量的倍增。
更新日期:2022-07-19
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