In article 2200029, Junjie Xiao and co-workers construct an artificial circular RNA named circmiR-29b as a specific molecular sponge for miR-29b. The artificial circmiR-29b treat muscle atrophy by suppressing miR-29b. As shown in the image, skeletal muscle is a super factory that produce protein and ATP. circmiR-29b mediate as molecular sponge like the powerful magnets which absorb miR-29b (arrows) and therefore protect the factory from arrows.

中文翻译：

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工程化环状 RNA CircmiR-29b 通过海绵化 MiR-29b 减轻肌肉萎缩（Adv. Therap. 7/2022）

在2200029号文章中，肖俊杰和同事构建了一种名为circmiR-29b的人工环状RNA，作为miR-29b的特异性分子海绵。人工 circmiR-29b 通过抑制 miR-29b 来治疗肌肉萎缩。如图所示，骨骼肌是生产蛋白质和ATP的超级工厂。circmiR-29b 像吸收 miR-29b（箭头）的强力磁铁一样作为分子海绵进行介导，从而保护工厂免受箭头的伤害。