Identification of Three Different Phenotypes in Anti–Melanoma Differentiation–Associated Gene 5 Antibody–Positive Dermatomyositis Patients: Implications for Prediction of Rapidly Progressive Interstitial Lung Disease,Arthritis & Rheumatology

当前位置： X-MOL 学术 › Arthritis Rheumatol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Identification of Three Different Phenotypes in Anti–Melanoma Differentiation–Associated Gene 5 Antibody–Positive Dermatomyositis Patients: Implications for Prediction of Rapidly Progressive Interstitial Lung Disease
Arthritis & Rheumatology ( IF 13.3 ) Pub Date : 2022-07-18 , DOI: 10.1002/art.42308
Lingxiao Xu ₁ , Hanxiao You ₁ , Lei Wang ₁ , Chengyin Lv ₁ , Fenghong Yuan ₂ , Ju Li ₃ , Min Wu ₄ , Zhanyun Da ₅ , Hua Wei ₆ , Wei Yan ₆ , Lei Zhou ₇ , Songlou Yin ₈ , Dongmei Zhou ₈ , Jian Wu ₉ , Yan Lu ₁₀ , Dinglei Su ₁₁ , Zhichun Liu ₁₂ , Lin Liu ₁₃ , Longxin Ma ₁₄ , Xiaoyan Xu ₁₅ , Yinshan Zang ₁₆ , Huijie Liu ₁₇ , Tianli Ren ₁₈ , Fang Wang ₁₉ , Yan Du ₂₀ , Jing Xue ₂₀ , Miaojia Zhang ₁ , Wenfeng Tan ₁

Affiliation

Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Department of Rheumatology and Immunology, Wuxi People's Hospital, Wuxi, China.
Department of Rheumatology and Immunology, Huai'an First People's Hospital, Huai'an, Jiangsu, China.
Department of Rheumatology and Immunology, The First People's Hospital of Changzhou, Changzhou, China.
Department of Rheumatology and Immunology, Affiliated Hospital of Nantong University, Nantong, China.
Department of Rheumatology and Immunology, Northern Jiangsu People's Hospital, Yangzhou, China.
Department of Rheumatology and Immunology, Changzhou No. 2 People's Hospital, Changzhou, China.
Department of Rheumatology and Immunology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Department of Rheumatology and Immunology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Department of Rheumatology and Immunology, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Department of Rheumatology and Immunology, Nanjing First Hospital, Nanjing, China.
Department of Rheumatology and Immunology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Department of Rheumatology and Immunology, Xuzhou Central Hospital, Xuzhou, China.
Department of Rheumatology and Immunology, Yancheng No. 1 People's Hospital, Yancheng, China.
Department of Rheumatology and Immunology, Zhongda Hospital Southeast University, Nanjing, China.
Department of Rheumatology and Immunology, The Affiliated Suqian First People's Hospital of Nanjing Medical University, Suqian, China.
Department of Rheumatology and Immunology, The First People's Hospital of Lianyungang, Lianyungang, China.
Department of Rheumatology and Immunology, Wuxi No. 2 People's Hospital, Wuxi, China.
Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Department of Rheumatology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

There is substantial heterogeneity among the phenotypes of patients with anti–melanoma differentiation–associated gene 5 antibody–positive (anti-MDA5+) dermatomyositis (DM), hindering disease assessment and management. This study aimed to identify distinct phenotype groups in patients with anti-MDA5+ DM and to determine the utility of these phenotypes in predicting patient outcomes.

中文翻译：

抗黑色素瘤分化相关基因 5 抗体阳性皮肌炎患者三种不同表型的鉴定：对预测快速进展性间质性肺病的意义

抗黑色素瘤分化相关基因 5 抗体阳性（抗 MDA5+）皮肌炎 (DM) 患者的表型存在显着异质性，阻碍了疾病评估和治疗。本研究旨在识别抗 MDA5+ DM 患者的不同表型组，并确定这些表型在预测患者预后中的效用。

更新日期：2022-07-18

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>