Previous observational studies demonstrated that a subset of patients with systemic lupus erythematosus (SLE) have markedly short telomere length in leukocytes. This study was undertaken to test whether leukocyte telomere length is causally associated with risk of SLE.

中文翻译：

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系统性红斑狼疮的端粒长度和发育：一项孟德尔随机研究

先前的观察性研究表明，一部分系统性红斑狼疮 (SLE) 患者的白细胞端粒长度明显较短。本研究旨在检验白细胞端粒长度是否与系统性红斑狼疮的风险存在因果关系。