As the leading cause of death worldwide, cardiovascular diseases (CVDs) present major challenges for health systems. In this study, we analyzed the effects of better population blood pressure control in the context of a proposed 80-80-80 target: 80% of individuals with hypertension are screened and aware of their diagnosis; 80% of those who are aware are prescribed treatment; and 80% of those on treatment have achieved guideline-specified blood pressure targets. We developed a population CVD model using country-level evidence on CVD rates, blood pressure levels and hypertension intervention coverage. Under realistic implementation conditions, most countries could achieve 80-80-80 targets by 2040, reducing all-cause mortality by 4–7% (76–130 million deaths averted over 2022–2050) and slowing the rise in CVD expected from population growth and aging (110–200 million cases averted). Although populous middle-income countries would account for most of the reduced CVD cases and deaths, low-income countries would experience the largest reductions in disease rates.

作为全球主要的死亡原因，心血管疾病 (CVDs) 对卫生系统提出了重大挑战。在这项研究中，我们分析了在提议的 80-80-80 目标背景下更好地控制人群血压的效果：80% 的高血压患者接受了筛查并了解他们的诊断；80% 的知情者接受了处方治疗；80% 的接受治疗者达​​到了指南指定的血压目标。我们利用国家层面关于 CVD 发生率、血压水平和高血压干预覆盖率的证据开发了一个人口 CVD 模型。在现实的实施条件下，大多数国家到 2040 年可以实现 80-80-80 的目标，将全因死亡率降低 4-7%（在 2022-2050 年期间避免了 76-1.3 亿例死亡），并减缓了因人口增长和老龄化而导致的 CVD 上升（避免了 1.10-2 亿例）。尽管人口众多的中等收入国家将占 CVD 病例和死亡人数减少的大部分，但低收入国家的发病率下降幅度最大。