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Evaluation of Effects of Titanium Dioxide and Zinc Oxide Nanoparticles on Baker’s Yeast (Saccharomyces cerevisiae) Glutathione Reductase Activities
Bulletin of Environmental Contamination and Toxicology ( IF 2.7 ) Pub Date : 2022-07-16 , DOI: 10.1007/s00128-022-03583-7
Hasan Karadag 1 , Beytullah Atkan 1
Affiliation  

The glutathione reductase (GR) of baker’s yeast (Saccharomyces cerevisiae) was exposed to titanium dioxide nanoparticles (TiO2 NPs) and zinc oxide nanoparticles (ZnO NPs) at concentrations of 0, 25, 50, 100, 250, and 500 mg/L (ppm) in vitro. According to the calculations, the effect of 25, 50, 100, 250, and 500 mg/L TiO2 NPs on GR enzyme activities resulted in percentage changes of − 3.12; − 0.87; − 2.12; − 2.12, and − 1.50, respectively. Percentage changes in GR enzyme activities with the effect of 25, 50, 100, 250, and 500 mg/L ZnO NPs were calculated as − 2.01; + 1.88; + 0.38; − 2.51, and + 0.75, respectively. It can be deduced from this research that the change in concentrations of TiO2 NPs and ZnO NPs has no statistically significant effect on GR enzyme activities in comparison with the control groups (p > 0.05, N = 3).



中文翻译:

评价二氧化钛和氧化锌纳米颗粒对面包酵母(酿酒酵母)谷胱甘肽还原酶活性的影响

将面包酵母 ( Saccharomyces cerevisiae )的谷胱甘肽还原酶 (GR)暴露于浓度为 0、25、50、100、250 和 500 mg/L的二氧化钛纳米粒子 (TiO 2 NPs) 和氧化锌纳米粒子 (ZnO NPs) (ppm) 体外。根据计算,25、50、100、250 和 500 mg/L TiO 2 NPs 对 GR 酶活性的影响导致 - 3.12 的百分比变化;- 0.87;- 2.12;− 2.12 和 − 1.50,分别。在 25、50、100、250 和 500 mg/L ZnO NPs 的影响下,GR 酶活性的百分比变化计算为 - 2.01;+ 1.88; + 0.38; − 2.51 和 + 0.75,分别。由本研究可知,TiO 2浓度的变化与对照组相比,NPs 和 ZnO NPs 对 GR 酶活性没有显着影响(p  > 0.05,N = 3)。

更新日期:2022-07-17
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