The glutathione reductase (GR) of baker’s yeast (Saccharomyces cerevisiae) was exposed to titanium dioxide nanoparticles (TiO₂ NPs) and zinc oxide nanoparticles (ZnO NPs) at concentrations of 0, 25, 50, 100, 250, and 500 mg/L (ppm) in vitro. According to the calculations, the effect of 25, 50, 100, 250, and 500 mg/L TiO₂ NPs on GR enzyme activities resulted in percentage changes of − 3.12; − 0.87; − 2.12; − 2.12, and − 1.50, respectively. Percentage changes in GR enzyme activities with the effect of 25, 50, 100, 250, and 500 mg/L ZnO NPs were calculated as − 2.01; + 1.88; + 0.38; − 2.51, and + 0.75, respectively. It can be deduced from this research that the change in concentrations of TiO₂ NPs and ZnO NPs has no statistically significant effect on GR enzyme activities in comparison with the control groups (p > 0.05, N = 3).

将面包酵母 ( Saccharomyces cerevisiae )的谷胱甘肽还原酶 (GR)暴露于浓度为 0、25、50、100、250 和 500 mg/L的二氧化钛纳米粒子 (TiO ₂ NPs) 和氧化锌纳米粒子 (ZnO NPs) (ppm) 体外。根据计算，25、50、100、250 和 500 mg/L TiO ₂ NPs 对 GR 酶活性的影响导致 - 3.12 的百分比变化；- 0.87；- 2.12；− 2.12 和 − 1.50，分别。在 25、50、100、250 和 500 mg/L ZnO NPs 的影响下，GR 酶活性的百分比变化计算为 - 2.01；+ 1.88; + 0.38; − 2.51 和 + 0.75，分别。由本研究可知，TiO _{2浓度的变化}与对照组相比，NPs 和 ZnO NPs 对 GR 酶活性没有显着影响（p  > 0.05，N = 3）。