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Analysis of morbidity and mortality in patients with primary bone tumors who underwent sacrectomy: A systematic review
Journal of Bone Oncology ( IF 3.1 ) Pub Date : 2022-07-16 , DOI: 10.1016/j.jbo.2022.100445
Mayara Branco E Silva 1 , Mayara Branco E Silva 1 , Samilly Conceição Maia Martins 1 , Karen Voltan Garofo 1 , Carlos Eduardo Hideo Hanasilo 1 , Mauricio Etchebehere 1
Affiliation  

Background

Sacrectomy is indicated for the resection of life-threatening tumors in the sacrum area. Several studies have been conducted to investigate important aspects of sacrectomy to help reduce the morbidity and mortality of patients who underwent the procedure. This aim of this systematic review was to highlight the prognoses of patients who underwent sacrectomy for the resection of primary bone tumors by analyzing information related to the intraoperative and perioperative periods of the procedure.

Methodology

Several databases were searched for relevant articles using the keywords “sacrectomy” and “survival” associated with the Boolean operators “or” and “and” ([SACRECTOMY OR SACRECTOM*] AND SURVIVAL).

Results

A total of 13 articles were selected for data collection. The studies reported in the articles included a total of 384 patients, 140 of whom underwent partial sacrectomy, whereas 244 underwent total sacral resections. The results of the analysis indicated that the average volume of blood lost during a resection performed using the combined anterior and posterior approaches (average duration, 8.35 h) was 4571.94 mL. Regarding poor outcomes and adverse events in the included studies, 10 patients died in the early postoperative period, whereas four patients had hemorrhagic shock. The most prevalent complications reported were surgical wound infection and sphincter dysfunction.

Conclusion

The optimal surgical approach for sacrectomy depends on the location of the tumor. The anterior approach, preferably with laparoscopy, is currently widely used to reduce the amount of blood lost during the procedure. Although the most prevalent complications of sacrectomy have a high incidence rate, the procedure has a low mortality rate.



中文翻译:

接受骶骨切除术的原发性骨肿瘤患者的发病率和死亡率分析:系统评价

背景

骶骨切除术适用于切除骶骨区域危及生命的肿瘤。已经进行了几项研究来调查骶骨切除术的重要方面,以帮助降低接受该手术的患者的发病率和死亡率。本系统评价的目的是通过分析与手术的术中和围手术期相关的信息来突出接受骶骨切除术以切除原发性骨肿瘤的患者的预后。

方法

使用与布尔运算符“或”和“和”([SACRECTOMY OR SACRECTOM*] AND SURVIVAL)相关的关键字“骶骨切除术”和“生存”搜索了几个数据库中的相关文章。

结果

共选择13篇文章进行数据收集。文章中报道的研究共包括 384 名患者,其中 140 人接受了部分骶骨切除术,而 244 人接受了全骶骨切除术。分析结果表明,在使用前后路联合手术(平均持续时间,8.35 小时)进行切除期间,平均失血量为 4571.94 毫升。关于纳入研究的不良结局和不良事件,10 名患者在术后早期死亡,而 4 名患者出现失血性休克。报告的最常见并发症是手术伤口感染和括约肌功能障碍。

结论

骶骨切除术的最佳手术方法取决于肿瘤的位置。前路入路,最好是腹腔镜,目前广泛用于减少手术过程中的失血量。尽管骶骨切除术最普遍的并发症发生率很高,但该手术的死亡率很低。

更新日期:2022-07-16
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