Objective: To determine the most effective non-pharmacological interventions to control the blood pressure variation in older hypertensive patients.

Methods: Primary endpoints were office systolic blood pressure (SBP) and diastolic blood pressure (DBP). The quality of evidence was assessed using the “risk of bias 2″ tool and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method. We performed a Bayesian network meta-analysis using R-4.0.2 software to compare the efficacy of interventions.

Results: 36 eligible studies (3,531 patients) with a median follow-up of 12 weeks, assessing 18 non-pharmacological interventions, were included. The percentages of high, moderate, low, and very low certainty evidence were 16.7%, 38.9%, 33.3%, and 11.1%, respectively.

Conclusion: High certainty evidence suggests that self-management education is most effective in lowering SBP and DBP in older patients with hypertension, followed by moderate-intensity aerobic exercise. Moderate-intensity resistance training is the most effective exercise for lowering SBP.

Registration: PROSPERO, #CRD42020209850.

目的：确定最有效的非药物干预措施来控制老年高血压患者的血压变化。

方法：主要终点是诊室收缩压（SBP）和舒张压（DBP）。使用“偏倚风险 2”工具和建议分级评估、制定和评估 (GRADE) 方法评估证据质量。我们使用 R-4.0.2 软件进行了贝叶斯网络荟萃分析，以比较干预措施的效果。

结果：纳入了 36 项符合条件的研究（3,531 名患者），中位随访时间为 12 周，评估了 18 种非药物干预措施。高、中、低和极低确定性证据的百分比分别为 16.7%、38.9%、33.3% 和 11.1%。

结论：高确定性证据表明，自我管理教育对降低老年高血压患者的 SBP 和 DBP 最有效，其次是中等强度的有氧运动。中等强度的抗阻训练是降低 SBP 最有效的运动。

注册：PROSPERO，#CRD42020209850。