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Intravesical Instillation of OnabotulinumtoxinA in the Treatment of Refractory Overactive Bladder in Participants with Urinary Incontinence.
The Journal of Urology ( IF 5.9 ) Pub Date : 2022-07-05 , DOI: 10.1097/ju.0000000000002800 Christopher J Chermansky 1 , Holly E Richter 2 , Karny Jacoby 3 , Wilson Titanji 4 , Brenda Jenkins 5 , Till Geib 5 , Benjamin M Brucker 6
The Journal of Urology ( IF 5.9 ) Pub Date : 2022-07-05 , DOI: 10.1097/ju.0000000000002800 Christopher J Chermansky 1 , Holly E Richter 2 , Karny Jacoby 3 , Wilson Titanji 4 , Brenda Jenkins 5 , Till Geib 5 , Benjamin M Brucker 6
Affiliation
Intradetrusor injections of onabotulinumtoxinA are efficacious for the treatment of overactive bladder with urgency urinary incontinence in adults refractory to, or intolerant of, anticholinergics. Delivery of onabotulinumtoxinA via instillation would reduce the need for intradetrusor injections. The objective of this trial was to assess the efficacy and safety of intravesical instillation of an onabotulinumtoxinA+hydrogel admixture.
中文翻译:
膀胱内滴注 OnabotulinumtoxinA 治疗尿失禁患者难治性膀胱过度活动症。
肌内注射肉毒杆菌毒素 A 可有效治疗抗胆碱能药物难治或不耐受的成人急迫性尿失禁膀胱过度活动症。通过滴注递送onabotulinumtoxinA 将减少对intratrusor 注射的需要。本试验的目的是评估膀胱内滴注肉毒杆菌毒素 A+水凝胶混合物的有效性和安全性。
更新日期:2022-07-05
中文翻译:
膀胱内滴注 OnabotulinumtoxinA 治疗尿失禁患者难治性膀胱过度活动症。
肌内注射肉毒杆菌毒素 A 可有效治疗抗胆碱能药物难治或不耐受的成人急迫性尿失禁膀胱过度活动症。通过滴注递送onabotulinumtoxinA 将减少对intratrusor 注射的需要。本试验的目的是评估膀胱内滴注肉毒杆菌毒素 A+水凝胶混合物的有效性和安全性。