Aim

Our aim was to determine the association of cardiopulmonary resuscitation (CPR) for in hospital cardiac arrest (IHCA) with quality of life after discharge.

Methods

We performed a systematic review using available databases for studies that measured any quality-of-life or functional outcome both before and after CPR for IHCA. All screening and data abstraction was performed in duplicate.

Results

We screened 10,927 records and included 24 papers representing 20 unique studies. Fifteen studies measured Cerebral Performance Category. Survival ranged from 11.8% to 39.5%. The risk of impaired cerebral function after discharged ranged from −16.1% (lower risk) to 44.7% increased risk of poor cerebral function after surviving to discharge. Four studies measured discharge to an institutional environment finding that the risk was increased by 18.2–72.2% among survivors. One study measured EQ-5D and found no difference pre and post CPR. One study measured performance of activities of daily living finding that survivors needed assistance with more activities after discharge.

Conclusion

Our review is limited by the lack of adjustment for confounders, including the baseline level of each outcome, in all included studies. Therefore, although risk for most outcomes was increased after discharge vs pre-admission we cannot be certain if this is a causal relationship.

中文翻译：

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院内心肺复苏后的生活质量和功能结果。系统评价

目标

我们的目的是确定院内心脏骤停 (IHCA) 的心肺复苏 (CPR) 与出院后生活质量的关系。

方法

我们使用现有数据库对 IHCA 的 CPR 前后测量任何生活质量或功能结果的研究进行了系统评价。所有筛选和数据提取一式两份进行。

结果

我们筛选了 10,927 条记录，包括代表 20 项独特研究的 24 篇论文。十五项研究测量了大脑性能类别。存活率为 11.8% 至 39.5%。出院后脑功能受损的风险范围从-16.1%（风险较低）到44.7%，存活出院后脑功能不良的风险增加。四项研究测量了出院到机构环境，发现幸存者的风险增加了 18.2-72.2%。一项研究测量了 EQ-5D，发现 CPR 前后没有差异。一项研究测量了日常生活活动的表现，发现幸存者在出院后需要更多活动的帮助。

结论

我们的审查受限于在所有纳入的研究中缺乏对混杂因素的调整，包括每个结果的基线水平。因此，尽管出院后与入院前相比，大多数结果的风险增加了，但我们无法确定这是否是因果关系。