Abstract

Trials of digital mental health interventions (DMHIs) often exclude individuals with suicide-related thoughts and behaviors precluding an understanding of whether DMHIs for affective disorders are safe for, and perform similarly within, this high-risk group. We explore the safety and performance of a DMHI for depression in participants with and without suicidal ideation (SI) at baseline. Three hundred and one participants were included in this secondary data analysis from a trial of an 8-week DMHI comprising 14 smartphone apps. We found that SI decreased across the study among participants with baseline SI and that baseline SI status did not attenuate depression treatment effects. Through a case study of the IntelliCare platform, we find that DMHIs for general affective disorders can be safe.

摘要

数字心理健康干预 (DMHI) 的试验通常会排除有自杀相关想法和行为的个体，从而妨碍了解用于治疗情感障碍的 DMHI 对于这个高风险群体是否安全，以及在该群体中是否表现相似。我们探讨了 DMHI 治疗基线时有或没有自杀意念 (SI) 的参与者的抑郁症的安全性和效果。这项二次数据分析涉及 301 名参与者，该数据分析来自一项为期 8 周的 DMHI 试验，其中包括 14 个智能手机应用程序。我们发现，在整个研究中，具有基线 SI 的参与者的 SI 有所下降，并且基线 SI 状态并没有减弱抑郁症治疗的效果。通过 IntelliCare 平台的案例研究，我们发现 DMHI 治疗一般情感障碍是安全的。