A simple and efficient electroactive modification matrix of silver nanoparticles (AgNPs), Mg-aminoclay (MgAC), and Materials of Institute Lavoisier (MIL)–53(Fe) was evaluated for an electrochemical sensor. The morphology, structure, and characterization of the proposed modification materials were assessed in detail using ultraviolet-visible light (UV-Vis) spectroscopy, X-ray powder diffraction, Raman spectroscopy, and transmission electron microscopy. The electrochemical properties and sensing performance of chloromycetin (CM), a broad-spectrum antibiotic drug that has numerous adverse effects, at the modified electrodes were measured using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Benefiting from possessing attractive chemical and physical properties, AgNPs synthesized from a simple reduction method were stabilized and homogeneously decorated on the MIL-53(Fe) framework owing to the presence of layered-MgAC nanomaterial, promising the increase in electrical conductivity, charge transferability, electrocatalytic activity, adsorption capability, and structural stability of the modified electrode (Ag-MgAC-MIL-53(Fe)/screen-printed electrode (SPE)). Under the optimized experimental condition, the concentration linear range was determined from 0.1–30 µM, corresponding to a rather low detection limit of 0.1 µM. This modified electrode had good repeatability, stability, and selectivity, demonstrating its high application potential in electrochemical sensors.

评估了一种由银纳米颗粒 (AgNPs)、镁氨基粘土 (MgAC) 和拉瓦锡研究所材料 (MIL)–53(Fe) 组成的简单有效的电活性改性基质，用于电化学传感器。使用紫外-可见光 (UV-Vis) 光谱、X 射线粉末衍射、拉曼光谱和透射电子显微镜对所提出的改性材料的形态、结构和表征进行了详细评估。使用循环伏安法 (CV) 和微分脉冲伏安法 (DPV) 测量了氯霉素 (CM) 的电化学性质和传感性能，该药物是一种具有多种不良反应的广谱抗生素药物。受益于拥有有吸引力的化学和物理特性，由于层状 MgAC 纳米材料的存在，通过简单还原方法合成的 AgNPs 在 MIL-53(Fe) 框架上被稳定和均匀修饰，有望提高导电性、电荷转移性、电催化活性、吸附能力和结构稳定性改性电极（Ag-MgAC-MIL-53（Fe）/丝网印刷电极（SPE））。在优化的实验条件下，浓度线性范围确定为 0.1–30 µM，对应于 0.1 µM 的相当低的检测限。该修饰电极具有良好的重复性、稳定性和选择性，显示出其在电化学传感器中的高应用潜力。有望提高修饰电极（Ag-MgAC-MIL-53（Fe）/丝网印刷电极（SPE））的电导率、电荷转移性、电催化活性、吸附能力和结构稳定性。在优化的实验条件下，浓度线性范围确定为 0.1–30 µM，对应于 0.1 µM 的相当低的检测限。该修饰电极具有良好的重复性、稳定性和选择性，显示出其在电化学传感器中的高应用潜力。有望提高修饰电极（Ag-MgAC-MIL-53（Fe）/丝网印刷电极（SPE））的电导率、电荷转移性、电催化活性、吸附能力和结构稳定性。在优化的实验条件下，浓度线性范围确定为 0.1–30 µM，对应于 0.1 µM 的相当低的检测限。该修饰电极具有良好的重复性、稳定性和选择性，显示出其在电化学传感器中的高应用潜力。对应于 0.1 µM 的相当低的检测限。该修饰电极具有良好的重复性、稳定性和选择性，显示出其在电化学传感器中的高应用潜力。对应于 0.1 µM 的相当低的检测限。该修饰电极具有良好的重复性、稳定性和选择性，显示出其在电化学传感器中的高应用潜力。