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More time awake after sleep onset is linked to reduced ventral striatum response to rewards in youth with anxiety
Journal of Child Psychology and Psychiatry ( IF 6.5 ) Pub Date : 2022-07-11 , DOI: 10.1111/jcpp.13669
Nathan A Sollenberger 1, 2 , Stefanie Sequeira 3 , Erika E Forbes 4 , Greg J Siegle 4 , Jennifer S Silk 3 , Cecile D Ladouceur 4 , Neal D Ryan 4 , Ronald E Dahl 5 , Aaron T Mattfeld 1, 2 , Dana L McMakin 1, 2
Affiliation  

Poor sleep and anxiety disorders are highly comorbid in youth, and each predicts altered ventral striatum (VS) response to rewards, which may impact mental health risk. Contrasting evidence suggests previously reported negative associations between sleep health and VS response may be stronger or weaker in youth with anxiety, indicating sensitivity to win/loss information or blunted reward processing, respectively. We cross-sectionally examined the role of sleep in VS response to rewards among youth with anxiety versus a no-psychiatric-diagnosis comparison (ND) group. We expected a group*sleep interaction on VS response to rewards but did not hypothesize directionality.

中文翻译:


入睡后清醒时间延长与患有焦虑症的青少年腹侧纹状体对奖励的反应减少有关



睡眠不佳和焦虑症在青少年中高度共存,两者都预示着腹侧纹状体(VS)对奖励的反应发生改变,这可能会影响心理健康风险。对比证据表明,先前报道的睡眠健康与 VS 反应之间的负相关在患有焦虑症的青少年中可能更强或更弱,分别表明对赢/输信息或迟钝的奖励处理的敏感性。我们横断面研究了睡眠在焦虑青少年与未精神病诊断比较(ND)组中对奖励的 VS 反应中的作用。我们预计 VS 对奖励的反应会出现群体*睡眠的相互作用,但没有假设方向性。
更新日期:2022-07-11
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