Cannabinoid compounds are being increasingly used as an analgesic adjuvant in the orthopedic population, but little data exist to either support or oppose this practice pattern. A review of all contemporary (2000–2020) studies on the use of cannabinoids in orthopedics is presented. Physicians and patients are optimistic that cannabinoids can decrease pain scores and perhaps opioid use; however, their application in orthopedics is not well characterized. In addition to the social stigma regarding the use of cannabis, there is limited high-quality evidence of the efficacy of cannabinoids in treating orthopedic-related pain. As cannabis becomes more accessible, well-designed trials are needed to better understand cannabinoids and guide orthopedic practice. [Orthopedics. 202x;xx(x):xx–xx.]

大麻素化合物越来越多地用作骨科人群的镇痛佐剂，但支持或反对这种实践模式的数据很少。对所有当代（2000-2020 年）关于在骨科中使用大麻素的研究进行了回顾。医生和患者对大麻素可以减少疼痛评分和阿片类药物的使用持乐观态度；然而，它们在整形外科中的应用还没有得到很好的表征。除了关于使用大麻的社会耻辱之外，关于大麻素治疗骨科相关疼痛疗效的高质量证据有限。随着大麻变得更容易获得，需要精心设计的试验来更好地了解大麻素并指导骨科实践。[骨科。202x;xx(x):xx–xx。]