We aimed to study the disparity in the clinical profile and outcomes of hospitalized Multisystem Inflammatory Syndrome in Children (MIS-C) patients at our center. The second goal was to examine the temporal association with preceding SARS-CoV-2 infection by race/ethnicity in our community in Mississippi. We found the racial disparity in the prevalence of MIS-C exceeded its temporal association with SARS-CoV-2 infections. We included 51 consecutive MIS-C patients hospitalized, whose median age was 9 (interquartile range [IQR] 5-12) years, 58% were male, 71% were black, 25% were white, and 4% belonged to other groups. We found a delay between onset of symptoms and hospitalization in black patients compared with white patients with a median of 2 (IQR 0-7) vs median of 0 (0-5) urgent care visits (P = .022), respectively. Black patients were hospitalized longer (median 8, IQR 2-39 days) than whites (median 5, IQR 3-14 days), P = .047. A total of 38.9% of blacks and 23.1% of whites were admitted to intensive care unit (P = .498); 36.1% of blacks had severe cardiac involvement vs 23.1% of white patients, P = .531. Future studies of MIS-C are required to improve health equity for children.

我们的目的是研究我们中心住院的儿童多系统炎症综合征 (MIS-C) 患者的临床特征和结果的差异。第二个目标是在我们密西西比州的社区中按种族/族裔检查与先前 SARS-CoV-2 感染的时间关联。我们发现 MIS-C 患病率的种族差异超过了其与 SARS-CoV-2 感染的时间关联。我们纳入了 51 名连续住院的 MIS-C 患者，中位年龄为 9（四分位间距 [IQR] 5-12）岁，58% 为男性，71% 为黑人，25% 为白人，4% 属于其他群体。我们发现黑人患者的症状发作和住院之间的延迟与白人患者相比，中位数为 2 (IQR 0-7) vs 中位数为 0 (0-5) 紧急护理就诊 ( P= .022），分别。黑人患者的住院时间（中位数 8，IQR 2-39 天）比白人（中位数 5，IQR 3-14 天）长，P = .047。共有 38.9% 的黑人和 23.1% 的白人被送入重症监护病房 ( P = .498)；36.1% 的黑人有严重的心脏受累，而白人患者为 23.1%，P = .531。未来需要对 MIS-C 进行研究，以改善儿童的健康公平性。