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When can we be confident of surgical cure with ctDNA?
Nature Reviews Clinical Oncology ( IF 81.1 ) Pub Date : 2022-07-07 , DOI: 10.1038/s41571-022-00664-8
Alexander Frankell 1, 2 , Mariam Jamal-Hanjani 1, 3, 4
Affiliation  

Tracking circulating tumour DNA (ctDNA) after surgery holds promise for patient management and therapeutic intervention in non-small-cell lung cancer (NSCLC). A study published by Zhang and colleagues tracks ctDNA from 261 patients with stages I–III NSCLC and suggests that the likelihood of disease relapse decreases for high-risk stage II/III patients after 18 months without ctDNA detection.

中文翻译:


我们什么时候才能有信心通过 ctDNA 进行手术治愈?



术后追踪循环肿瘤 DNA (ctDNA) 有望为非小细胞肺癌 (NSCLC) 的患者管理和治疗干预带来希望。张及其同事发表的一项研究追踪了 261 名 I-III 期 NSCLC 患者的 ctDNA,结果表明,在 18 个月没有检测到 ctDNA 的情况下,高危 II/III 期患者疾病复发的可能性会降低。
更新日期:2022-07-07
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